Collection: Chiral Heterocyclic Building Blocks

Chiral Heterocyclic Building Blocks — a collection of heterocyclic compounds with single or multiple stereogenic centers, including tetrahydrofuran, oxazolidine, azetidine, and oxygen-nitrogen bicyclic derivatives in defined (R) or (S) configurations. This group provides ready-to-use chiral frameworks for asymmetric synthesis that preserve stereochemical integrity.

Chiral Heterocyclic Building Blocks are used by synthetic chemists and pharmaceutical chemistry researchers in asymmetric synthesis to build target molecules with controlled stereochemistry, including as intermediates in the preparation of highly complex multistep compounds. Boc-protected and oxazolidine dicarboxylate derivatives are commonly used as chiral auxiliaries or substrates for diastereoselective reactions, while chiral tetrahydrofuran amines serve as building blocks for forming new stereogenic centers through substitution or reduction reactions.

Example products in this collection: TCI T4385 111769-26-7 (R)-Tetrahydrofuran-3-amine, TCI B5538 1013028-26-6 3-tert-Butyl 4-Methyl (4R,5S)-2,2,5-Trimethyloxazolidine-3,4-dicarboxylate, TCI T2902 97538-67-5 (2R,5S)-2-Trichloromethyl-3-oxa-1-azabicyclo[3.3.0]octan-4-one, TCI B5657 108149-65-1 tert-Butyl (S)-4-(Hydroxymethyl)-2,2-dimethyloxazolidine-3-carboxylate, TCI T2552 7175-81-7 (S)-(+)-Tetrahydrofurfurylamine, TCI B5682 877399-00-3 (R)-5-Bromo-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine, TCI T2551 7202-43-9 (R)-(-)-Tetrahydrofurfurylamine, TCI B6343 51077-14-6 (S)-1-(tert-Butoxycarbonyl)azetidine-2-carboxylic Acid.

Pay attention to the stereochemical configuration (R or S) and the optical purity (ee) suited to the synthesis requirements, and the status of protecting groups (such as Boc) that determine compatibility with the next reaction step. All products are genuine products of Tokyo Chemical Industry (TCI) Japan, with purity, packaging, and storage conditions listed on each item's page.

Other categories aligned under Chiral Building Blocks, often used together in a single laboratory workflow:

• Chiral Non-Heterocyclic Building Blocks
• Privileged Ligands and Complexes [Asymmetric Synthesis]
• Hydrogenation [Asymmetric Synthesis]

Back to Chiral Building Blocks. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official TCI Japan distributor in Indonesia — for availability checks and direct lead times from Japan.