HPLC Ion-Pair Reagents for Basic Samples

HPLC Ion-Pair Reagents for Basic Samples — contains long-chain alkyl sulfonate salts, ranging from sodium dodecyl sulfonate to nonanesulfonate, which function as ion-pairing reagents in liquid chromatography mobile phases. This group is specifically designed to enhance the retention of basic analytes on reversed-phase columns.

Ion-pair reagents such as Sodium 1-Dodecanesulfonate and Sodium 1-Decanesulfonate are added to the HPLC mobile phase to form neutral ion pairs with ionized basic compounds, so that their interaction with the C18 stationary phase becomes stronger and more predictable. Analysts in pharmaceutical and quality control laboratories use variations in alkyl chain length, from Sodium 1-Nonanesulfonate to Sodium Dodecyl Sulfate, to optimize the separation resolution of amines, alkaloids, or other basic compounds.

Example products in this collection: TCI I0352 151-21-3 Sodium Dodecyl Sulfate [Reagent for Ion-Pair Chromatography], TCI I0341 14533-63-2 Sodium 1-Propanesulfonate [Reagent for Ion-Pair Chromatography], TCI I0351 5802-89-1 Sodium 1-Tridecanesulfonate [Reagent for Ion-Pair Chromatography], TCI I0342 2386-54-1 Sodium 1-Butanesulfonate [Reagent for Ion-Pair Chromatography], TCI I0350 2386-53-0 Sodium 1-Dodecanesulfonate [Reagent for Ion-Pair Chromatography], TCI I0343 22767-49-3 Sodium 1-Pentanesulfonate [Reagent for Ion-Pair Chromatography], TCI I0349 5838-34-6 Sodium 1-Undecanesulfonate [Reagent for Ion-Pair Chromatography], TCI I0344 2832-45-3 Sodium 1-Hexanesulfonate [Reagent for Ion-Pair Chromatography].

Choose the carbon chain length according to the analyte retention requirements, and pay attention to the HPLC grade purity to avoid baseline disturbance or contamination in UV or MS detection. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other categories at the same level under Ion Pair Reagents (for HPLC), often used together in a single laboratory workflow:

Back to Ion Pair Reagents (for HPLC). For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — the official TCI Japan distributor in Indonesia — to check availability and lead time directly from Japan.

11 products