Collection: HPLC Ion-Pair Reagents for Acidic Samples

HPLC Ion-Pair Reagents for Acidic Samples — covers long-chain alkyl quaternary ammonium salts and bases (tetrabutyl-, tetrapropyl-, dodecyltrimethyl-ammonium) that function as ion-pair reagents in liquid chromatography. This group serves to enhance interaction with charged analytes on reversed-phase columns.

HPLC analysts use these ion-pair reagents to improve retention and separation resolution of negatively charged compounds (carboxylic acids, sulfonic acids, or other anions) on reversed-phase columns, by forming neutral ion pairs with the anionic analytes. Selecting quaternary ammonium cations with different alkyl chain lengths or counter-anions (phosphate, hydroxide, chloride, bromide, hydrogen sulfate) allows optimization of separation method selectivity for diverse acidic samples.

Product examples in this collection: TCI I0367 5574-97-0 Tetrabutylammonium Phosphate (05mol/L in Water) [Reagent for Ion-Pair Chromatography], TCI I0363 77-98-5 Tetraethylammonium Hydroxide (10% in Water) [Reagent for Ion-Pair Chromatography], TCI I1130 4499-86-9 Tetrapropylammonium Hydroxide (10% in Water) [Reagent for Ion-Pair Chromatography], TCI I0364 2052-49-5 Tetrabutylammonium Hydroxide (10% in Water) [Reagent for Ion-Pair Chromatography], TCI I1129 14937-42-9 Tetra(decyl)ammonium Bromide [Reagent for Ion-Pair Chromatography], TCI I0365 1643-19-2 Tetrabutylammonium Bromide [Reagent for Ion-Pair Chromatography], TCI I0453 112-00-5 Dodecyltrimethylammonium Chloride [Reagent for Ion-Pair Chromatography], TCI I0366 1112-67-0 Tetrabutylammonium Chloride [Reagent for Ion-Pair Chromatography].

Pay attention to the reagent form (ready-to-use solution in water or solid/salt form), the type of counter-anion, and the alkyl chain length of the ammonium cation, which affect the strength of the ion pair formed. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other parallel categories under Ion Pair Reagents (for HPLC), often used together in one laboratory workflow:

• HPLC Ion-Pair Reagents for Basic Samples
• LC/MS Ion-Pair Reagents for Basic Samples
• LC/MS Ion-Pair Reagents for Acidic Samples
• HPLC Fluorimetric Ion-Pair Reagent

Back to Ion Pair Reagents (for HPLC). For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official distributor of TCI Japan in Indonesia — to check availability and lead time directly from Japan.