Collection: LC/MS Ion-Pair Reagents for Basic Samples

LC/MS Ion-Pair Reagents for Basic Samples — contains short- to medium-chain perfluorocarboxylic acids such as trifluoroacetic acid, nonafluorovaleric acid, undecafluorohexanoic acid, and tridecafluoroheptanoic acid, available as ready-to-use solutions as well as high grade. This reagent group forms ion pairs with positively charged analytes in chromatographic separation systems.

These perfluorocarboxylic acid ion-pair reagents are used by analytical researchers in LC-MS methods to improve retention and separation resolution of basic compounds such as peptides or amines on reversed-phase columns. The choice of fluorocarbon chain length affects the strength of the ion pair, so it is adjusted to the basicity of the analyte and the desired mass detection sensitivity.

Example products in this collection: TCI A5711 76-05-1 Trifluoroacetic Acid (ca. 0.5mol/L in Water) [Ion-Pair Reagent for LC-MS], TCI A5712 422-64-0 Pentafluoropropionic Acid (ca. 0.5mol/L in Water) [Ion-Pair Reagent for LC-MS], TCI A5722 307-24-4 Undecafluorohexanoic Acid High Grade [Ion-Pair Reagent for LC-MS], TCI A5713 375-22-4 Heptafluorobutyric Acid (ca. 0.5mol/L in Water) [Ion-Pair Reagent for LC-MS], TCI A5721 375-85-9 Tridecafluoroheptanoic Acid High Grade [Ion-Pair Reagent for LC-MS], TCI A5714 2706-90-3 Nonafluorovaleric Acid (ca. 0.5mol/L in Water) [Ion-Pair Reagent for LC-MS], TCI A5716 375-85-9 Tridecafluoroheptanoic Acid (ca. 5mmol) [Ion-Pair Reagent for LC-MS], TCI A5715 307-24-4 Undecafluorohexanoic Acid (ca. 5mmol) [Ion-Pair Reagent for LC-MS].

Please pay attention to the perfluoro chain length and solution concentration (for example about 0.5 mol/L or 5 mmol) according to method requirements, and choose high grade when a cleaner background spectrum in LC-MS is needed. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other categories at the same level under Ion Pair Reagents (for HPLC), often used together in one laboratory workflow:

• HPLC Ion-Pair Reagents for Basic Samples
• HPLC Ion-Pair Reagents for Acidic Samples
• LC/MS Ion-Pair Reagents for Acidic Samples
• HPLC Fluorimetric Ion-Pair Reagent

Back to Ion Pair Reagents (for HPLC). For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official TCI Japan distributor in Indonesia — to check availability and lead time directly from Japan.