LC/MS Ion-Pair Reagents for Acidic Samples

LC/MS Ion-Pair Reagents for Acidic Samples — a collection of dialkylammonium acetate salt solutions with various alkyl chain lengths (propyl to hexyl), which function as volatile ion-pair reagents to improve retention and resolution of acidic analytes in LC/MS analysis.

These ion-pair reagents are used by bioanalysis researchers and LC/MS method developers to improve peak shape and retention of acidic compounds such as organic acids, nucleotides, or polar metabolites on reversed-phase columns. Because they are volatile, the salts from dipropylammonium to dihexylammonium acetate are compatible with electrospray ionization sources and do not interfere with mass detection sensitivity, and they are selected based on the hydrophobicity required for optimal ion pairing.

Example products in this collection: TCI A5705 366793-17-1 Dihexylammonium Acetate (ca. 0.5mol/L in Water) [Ion-Pair Reagent for LC-MS], TCI A5702 19070-91-8 Dibutylammonium Acetate (ca. 0.5mol/L in Water) [Ion-Pair Reagent for LC-MS], TCI A5704 211676-91-4 Diamylammonium Acetate (ca. 0.5mol/L in Water) [Ion-Pair Reagent for LC-MS], TCI A5703 114389-69-4 Dipropylammonium Acetate (ca. 0.5mol/L in Water) [Ion-Pair Reagent for LC-MS].

Reagent selection should be matched to the hydrophobicity of the target analytes, the required solution concentration, and compatibility with the electrospray ionization source of the LC/MS instrument in use. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other parallel categories under Ion Pair Reagents (for HPLC), often used together in one laboratory workflow:

Back to Ion Pair Reagents (for HPLC). For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — the official TCI Japan distributor in Indonesia — to check availability and lead time directly from Japan.

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