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CAS 8048-52-0

Acriflavine (mixture of 3,6-Diamino-10-methylacridinium Chloride and 3,6-Diaminoacridine) TCI A0134

Acriflavine (mixture of 3,6-Diamino-10-methylacridinium Chloride and 3,6-Diaminoacridine) TCI A0134

Chemical Identity

CAS No.
8048-52-0
PubChem
CID 443101·SID 87561825
Formula
C27H25ClN6
Molecular weight
469.0 g/mol
Purity
>70.0%(HPLC)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
acridine-3,6-diamine;10-methylacridin-10-ium-3,6-diamine;chloride
SMILES
C[N+]1=C2C=C(C=CC2=CC3=C1C=C(C=C3)N)N.C1=CC(=CC2=NC3=C(C=CC(=C3)N)C=C21)N.[Cl-]
InChIKey
PEJLNXHANOHNSU-UHFFFAOYSA-N
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Acriflavine is a chemical compound widely used in laboratory settings, particularly in biochemistry and pharmacology. It is a mixture of 3,6-Diamino-10-methylacridinium Chloride and 3,6-Diaminoacridine, both of which exhibit antimicrobial properties. This compound is commonly employed for bacterial identification and as a reagent in biological testing processes. Its role is critical in microbiological and pharmacological research, where accurate and reliable results are essential. Acriflavine is valued for its stability and ease of measurement, making it a preferred choice for specialized reagent applications.

The chemical properties of Acriflavine allow it to interact with various biological substrates, including proteins and DNA. It is soluble in organic solvents and maintains stability under specific conditions, which contributes to its reliability in laboratory experiments. Its ability to bind to nucleic acids and proteins makes it useful in staining and analytical techniques. These characteristics make Acriflavine a versatile tool in both research and diagnostic applications.

In Indonesian laboratories, Acriflavine is utilized in a range of studies related to public health, pharmaceutical development, and biotechnology. It is commonly applied in antimicrobial activity testing and biological analysis. Its availability and effectiveness make it a standard reagent in many research institutions and academic settings. The compound's consistent performance supports its use in both basic and applied research projects.

  • Antimicrobial Activity Testing – Acriflavine is used to evaluate the effectiveness of antimicrobial agents against various bacterial strains due to its inherent antimicrobial properties.
  • Bacterial Identification – Its ability to bind to nucleic acids makes it useful in staining techniques for identifying bacterial species in microbiological studies.
  • Biological Staining – Acriflavine is employed in cellular and tissue staining applications, aiding in the visualization of biological structures under a microscope.
  • Pharmacological Research – It serves as a reagent in drug development studies, helping to assess the interaction of compounds with biological molecules.
  • Diagnostic Testing – Acriflavine is used in diagnostic assays to detect microbial presence in samples, supporting clinical and research applications.

Brand TCI
CAS number 8048-52-0
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Antibiotics
Pack sizes Available in standard laboratory quantities
Physical form Solid powder
Storage Store in a cool, dry place away from light

Acriflavine should be stored in a cool, dry place, away from direct light to maintain its stability and effectiveness. It is recommended to use airtight containers to prevent moisture absorption and contamination. As a chemical compound, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. Due to its chemical nature, it should be stored separately from incompatible substances. In laboratory settings, proper ventilation is essential when handling this compound to ensure a safe working environment. Regular inspection of storage conditions is necessary to ensure the integrity of the material over time.

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