Aminoacetal TCI A0247

Chemical Identity

CAS No.: 645-36-3
PubChem: CID 69524·SID 87561904
Formula: C6H15NO2
Molecular weight: 133.19 g/mol
Purity: >97.0%(GC)(T)
Reference databases: ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 2,2-diethoxyethanamine
SMILES: CCOC(CN)OCC
InChIKey: HJKLEAOXCZIMPI-UHFFFAOYSA-N

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Volume 25mL 250mL

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Dokumen Keamanan & Mutu

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CoA (Certificate of Analysis)

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Aminoacetal from TCI, also known as aminoacetaldehyde diethyl acetal, is a bifunctional organic building block. In one small molecule it combines a primary amine group with an aldehyde group protected as an acetal. This combination makes it a valuable intermediate in organic synthesis, especially for building nitrogen-containing rings at later stages of a synthetic route. Medicinal chemistry, natural product synthesis and pharmaceutical research laboratories use it as a starting point for assembling more complex molecular frameworks in a controlled way.

The main advantage of Aminoacetal is its masked aldehyde. While the acetal stays intact, the amine group can be reacted selectively, for example by acylation, alkylation or condensation with carbonyl compounds, without interference from a reactive free aldehyde. Acid treatment can then open the acetal and release the aldehyde, which can drive a cyclization or a further transformation. This stepwise approach gives chemists better control over the order of reactions and helps reduce unwanted side products, which is why many synthetic groups prefer it over unprotected alternatives.

In Indonesia, Aminoacetal is relevant to university organic chemistry research groups, pharmaceutical development laboratories and institutions working on bioactive compounds and heterocycle synthesis. Researchers use it in multistep synthesis projects, thesis and dissertation work, and method development where predictable reactivity matters. Because it comes from TCI, a well-known brand in research chemicals, laboratories can work with consistent material from batch to batch and plan their synthetic campaigns with confidence.

Related TCI products

Heterocycle synthesis: the amine can be functionalized first, then acid-mediated acetal cleavage releases the aldehyde to close nitrogen-containing rings in a controlled sequence.
Medicinal chemistry scaffold building: its bifunctional structure lets chemists add substituents step by step while building more complex drug-like frameworks for structure–activity studies.
Natural product synthesis: the protected aldehyde stays inert through early steps and can be revealed at the right point in long, multistep synthetic routes.
Selective amine derivatization: acylation, alkylation or condensation with carbonyl compounds can be done on the amine without side reactions from a free aldehyde group.
Teaching and method development: it clearly shows protecting-group strategy and sequential reactivity, which suits advanced organic chemistry coursework and new methodology research.

Brand	TCI (product code A0247)
CAS number	645-36-3
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes	as listed on the product page
Physical form	refer to the TCI product specification and certificate of analysis
Storage	tightly closed container in a cool, dry, well-ventilated place

Store Aminoacetal in its original tightly sealed container in a cool, dry, well-ventilated area, away from heat sources, direct sunlight and moisture. Keep it separate from acids and strong oxidizing agents, because acidic conditions can cleave the acetal group. Use chemically compatible glass or approved containers when transferring the material. Handle it in a fume hood and wear safety goggles, chemical-resistant gloves and a lab coat. Avoid inhalation and contact with skin or eyes. Always read the supplier's Safety Data Sheet before use and dispose of waste according to local regulations.

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