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TCI

CAS 51-55-8

Atropine TCI A0754

Atropine TCI A0754

Chemical Identity

CAS No.
51-55-8
PubChem
CID 3661·SID 87562295
Formula
C17H23NO3
Molecular weight
289.4 g/mol
Purity
>99.0%(T)
Reference databases
ChEBI·ChemSpider
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenylpropanoate
SMILES
CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3
InChIKey
RKUNBYITZUJHSG-UHFFFAOYSA-N
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Atropine, with CAS number 51-55-8, is a widely used alkaloid in life science laboratories. It is a key compound in biochemical and pharmacological research due to its ability to block acetylcholine receptors. This compound plays a crucial role in studying the effects of neurotransmitters on the parasympathetic nervous system. Its anticholinesterase activity makes it an essential tool for evaluating physiological responses to neural stimulation. Atropine is commonly found in experiments related to the nervous system, drug effects, and pharmacological mechanisms. Its presence in various research fields highlights its versatility and importance in scientific studies.

Atropine is preferred for its selective muscarinic receptor blockade and chemical stability. It is available in powder or liquid form, depending on packaging, and remains chemically stable under appropriate storage conditions. Its non-colored appearance and consistent physical form make it reliable for use in controlled laboratory environments. The compound's ability to inhibit muscarinic receptors without affecting other receptor types allows for targeted experimental applications. These properties ensure that atropine remains a trusted reagent in both academic and research settings.

In Indonesian laboratories, atropine is commonly used in educational institutions and research facilities. It is integral to studies involving the nervous system, cardiac effects, and gastrointestinal responses. Its role in pharmacological research and physiological studies makes it a staple in many laboratories across Indonesia. The compound's reliability and effectiveness contribute to its widespread use in both teaching and experimental research.

Advantages (TCI brochure)

  • Tropane alkaloid first extracted from the root of belladonna (Atropa belladonna) in the 1830s
  • Competitive antagonist of muscarine-like actions of acetylcholine
  • Classified as an antimuscarinic agent

TCI brochures (PDF)

  • Atropine is used in pharmacological research to study the effects of drugs on the nervous system due to its ability to block muscarinic receptors.
  • It is applied in cardiovascular studies to evaluate the impact of anticholinergic agents on heart rate and blood pressure.
  • Atropine is essential in gastrointestinal research for analyzing the effects of parasympathetic inhibition on digestion.
  • It is used in neuropharmacology to investigate the mechanisms of neurotransmitter action and receptor interactions.
  • The compound is employed in toxicology studies to assess the safety and efficacy of various compounds in biological systems.

Brand TCI
CAS number 51-55-8
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Alkaloids
Pack sizes Available in various quantities as per supplier specifications
Physical form Powder or liquid, depending on packaging
Storage Store in a cool, dry place away from light and moisture

Atropine should be stored in a cool, dry place, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent contamination and degradation. Due to its potency, proper handling is essential to avoid exposure. Laboratory personnel should wear appropriate personal protective equipment when handling the compound. Regular monitoring of storage conditions ensures the integrity of the product. Atropine is not flammable, but it should be kept out of reach of children and not mixed with incompatible substances. Proper labeling and storage practices are crucial for safe and effective use in laboratory settings.

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