Dimethyl Adipimidate Dihydrochloride [Cross-linking Agent for Protein Research] TCI A0806

Chemical Identity

CAS No.: 14620-72-5
PubChem: CID 12876176·SID 87562332
Formula: C8H18Cl2N2O2
Molecular weight: 245.14 g/mol
Purity: >98.0%(T)
Reference databases: ChemSpider·ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: dimethyl hexanediimidate;dihydrochloride
SMILES: COC(=N)CCCCC(=N)OC.Cl.Cl
InChIKey: IEUUDEWWMRQUDS-UHFFFAOYSA-N

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Dimethyl Adipimidate Dihydrochloride (DMADH) is a chemical compound widely used as a cross-linking agent in protein research. It plays a crucial role in laboratories by enabling the formation of disulfide bonds between protein molecules. This functionality is essential for studying protein structure, interactions, and modifications. As a key reagent in biochemical and biophysical studies, DMADH supports the development of vaccines, therapeutic proteins, and diagnostic tools. Its ability to create stable covalent bonds makes it an indispensable tool in modern molecular biology and biochemistry research.

DMADH is favored for its high reactivity and stability under controlled laboratory conditions. It exhibits strong cross-linking capabilities, allowing researchers to investigate protein-protein or protein-ligand interactions with precision. The compound’s chemical properties ensure consistent performance, making it a reliable choice for both academic and industrial research settings. Its efficiency in forming strong, specific bonds enhances the accuracy of experimental results, contributing to the advancement of biomedical science.

In Indonesian laboratories, DMADH is commonly used in biochemistry research, including structural protein analysis, pharmaceutical development, and biomedical studies. It is a vital component in experiments that require precise molecular interactions, supporting both fundamental research and applied scientific projects. Its widespread use underscores its importance in the scientific community, particularly in regions where protein research is a priority.

TCI brochures (PDF)

Cross-linkers 2026-04-14 · p. 2
Bioconjugation Reagents 2026-07-07 · p. 8
Reagents for Biological Research 2025-03-11 · p. 29

Related TCI products

Protein-protein interaction studies benefit from DMADH's ability to form stable cross-links, enabling detailed structural analysis and functional characterization.
Vaccine development utilizes DMADH to study antigen-antibody interactions and protein stabilization, enhancing immunological research outcomes.
Structural biology research employs DMADH to investigate protein folding and conformational changes, aiding in the design of therapeutic molecules.
Biomedical research applications leverage DMADH for modifying proteins to improve their therapeutic properties or diagnostic potential.
Pharmaceutical development uses DMADH to analyze protein-ligand interactions, supporting the optimization of drug candidates and formulations.

Brand	TCI
CAS number	14620-72-5
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes	Available in various quantities as per standard laboratory supply formats
Physical form	Solid powder
Storage	Store in a cool, dry place away from moisture and direct sunlight

DMADH should be stored in a cool, dry environment to maintain its chemical stability and reactivity. It is recommended to keep the compound in a sealed container to prevent exposure to moisture and air, which may affect its performance. Proper labeling of storage containers is essential for safe handling and easy identification. Laboratory personnel should wear appropriate personal protective equipment, such as gloves and safety goggles, when handling this compound. Avoid direct contact with skin or inhalation of vapors. Ensure adequate ventilation in the workspace to minimize any potential risks associated with its use.

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