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TCI

CAS 58626-38-3

N-Succinimidyl 3-Maleimidobenzoate [Cross-linking Reagent] TCI S0398

N-Succinimidyl 3-Maleimidobenzoate [Cross-linking Reagent] TCI S0398

Chemical Identity

CAS No.
58626-38-3
PubChem
CID 93861·SID 87575905
Formula
C15H10N2O6
Molecular weight
314.25 g/mol
Purity
>98.0%(HPLC)(N)
Reference databases
ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(2,5-dioxopyrrolidin-1-yl) 3-(2,5-dioxopyrrol-1-yl)benzoate
SMILES
C1CC(=O)N(C1=O)OC(=O)C2=CC(=CC=C2)N3C(=O)C=CC3=O
InChIKey
LLXVXPPXELIDGQ-UHFFFAOYSA-N
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TCI S0398 58626-38-3 N-Succinimidyl 3-Maleimidobenzoate is a cross-linking reagent widely used in laboratory settings for connecting proteins or other biomolecules during various experimental procedures. This compound plays a crucial role in molecular interaction studies, drug development, and protein structure analysis. As a cross-linking agent, it enables researchers to chemically link two molecules through specific reactions, facilitating the observation of molecular interactions in biological environments. Its utility spans across multiple scientific disciplines, making it an essential tool for biochemists and molecular biologists alike.

The compound is known for its chemical stability and high reactivity, which make it a preferred choice in chemical biology applications. Its molecular structure allows for reactions with both amino and thiol groups, making it suitable for linking proteins and other biomolecules. This reagent's ability to maintain the biological activity of the molecules it connects is a key advantage, especially in experiments requiring high precision. Its versatility and effectiveness contribute to its widespread use in both academic and industrial research settings.

In Indonesian laboratories, TCI S0398 58626-38-3 N-Succinimidyl 3-Maleimidobenzoate is commonly used in biomedical, pharmacological, and biotechnological research. It is a valuable resource for scientists working on protein-protein interactions, antibody labeling, and conjugation studies. Its reliability and performance make it a go-to reagent for researchers aiming to achieve accurate and reproducible results in their experiments.

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  • Protein-protein interaction studies benefit from this reagent as it allows for the specific and stable cross-linking of proteins, aiding in the analysis of molecular interactions.
  • Drug development research utilizes this compound to study how biomolecules interact with potential therapeutic agents, enhancing the understanding of drug mechanisms.
  • Antibody labeling and conjugation applications rely on its ability to react with amino and thiol groups, enabling the attachment of fluorescent or other markers to proteins.
  • Structural biology experiments use this reagent to determine the spatial arrangement of proteins by cross-linking key residues, providing insights into molecular architecture.
  • Biotransformation studies employ this cross-linking agent to investigate how proteins undergo modifications or interactions under different biochemical conditions.

Brand TCI
CAS number 58626-38-3
Molecular formula —
Purity —
Category Chemistry > Chemical Biology > Linkers and Crosslinkers
Pack sizes Available in various quantities as per supplier specifications
Physical form Solid or powder, depending on the packaging
Storage Store in a cool, dry place away from light and moisture

This reagent should be stored in a cool, dry place, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to air and humidity, which could affect its reactivity. Due to its chemical nature, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. It is important to keep the substance in a secure location, away from incompatible materials to avoid any potential chemical reactions. Proper labeling of storage containers is essential for safe handling and to prevent accidental exposure. Always follow standard laboratory safety protocols when working with cross-linking agents to ensure a safe and controlled environment.

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