3-Sulfo-N-succinimidyl 4-(N-Maleimidomethyl)cyclohexane-1-carboxylate Sodium Salt TCI S0883

Chemical Identity

CAS No.: 92921-24-9
PubChem: CID 4618794·SID 160871274
Formula: C16H17N2NaO9S
Molecular weight: 436.4 g/mol
Purity: >97.0%(qNMR)
Reference databases: ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: sodium 1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate
SMILES: C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)ON3C(=O)CC(C3=O)S(=O)(=O)[O-].[Na+]
InChIKey: VUFNRPJNRFOTGK-UHFFFAOYSA-M

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3-Sulfo-N-succinimidyl 4-(N-Maleimidomethyl)cyclohexane-1-carboxylate Sodium Salt is a chemical compound widely used in biochemical and biomedical research as a linker and crosslinker. This compound plays a crucial role in molecular conjugation by enabling covalent bonds between proteins and other biomolecules. Its unique structure allows for versatile applications in various laboratory settings, making it an essential tool for researchers working on protein analysis and modification. The compound's ability to form stable and specific linkages is particularly valuable in studies involving molecular interactions and functional assays.

The compound is preferred due to its high reactivity and the presence of two functional groups: the NHS ester and the maleimide group. These groups allow it to react with a wide range of biomolecules, including proteins, amino acids, and lipids. The combination of these reactive functionalities ensures that the compound can be used in multiple experimental setups, offering flexibility and reliability. Its stability under controlled conditions further enhances its suitability for use in laboratory environments where precision and reproducibility are critical.

In Indonesian laboratories, this compound is commonly used in biochemical and biomedical research. It supports various studies, including drug development, vaccine research, and protein analysis. Its availability in the local market facilitates research activities that require molecular crosslinking, enabling scientists to conduct experiments efficiently and effectively. The compound's role in advancing scientific research is well recognized among Indonesian researchers and institutions.

TCI brochures (PDF)

Copper-free Click Reaction Linkers 2026-04-30 · p. 2
Pre-Weighed Biotinylation Reagents 2025-03-25 · p. 2
Cross-linkers 2026-04-14 · p. 2
Protein and Biological Sample Preparation Reagents 2026-09-10 · p. 16
Drug Delivery System (DDS) Research Reagents 2025-01-29 · p. 3
Bioconjugation Reagents 2026-07-07 · p. 8

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Protein conjugation and labeling experiments benefit from this compound's ability to form stable covalent bonds with proteins and other biomolecules.
Crosslinking applications in immunology and biochemistry rely on its dual functional groups for precise molecular connections.
Diagnostic assay development utilizes its reactivity to link biomarkers to detection platforms, enhancing sensitivity and specificity.
Molecular imaging studies use it to attach fluorescent or radioactive tags to proteins for tracking and analysis.
Drug conjugation research employs its crosslinking properties to create targeted therapeutics for improved delivery and efficacy.

Brand	TCI
CAS number	92921-24-9
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Linkers and Crosslinkers
Pack sizes	Available in various quantities as per standard laboratory requirements
Physical form	Solid powder
Storage	Store at controlled room temperature, away from moisture and light

This compound should be stored in a cool, dry place, away from direct sunlight and moisture to maintain its stability and reactivity. It is recommended to keep it in a sealed container to prevent exposure to humidity, which could affect its performance. In a laboratory setting, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure safe handling. The compound is not flammable but should be stored separately from incompatible substances to avoid any potential chemical interactions. Regular monitoring of storage conditions is advised to ensure the integrity of the material remains unaffected over time. Proper labeling and storage practices are essential to maintain a safe and efficient laboratory environment.

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