N-Succinimidyl 3-Maleimidopropionate [Cross-linking Reagent] TCI S0427

Chemical Identity

Other names: BMPS
CAS No.: 55750-62-4
PubChem: CID 4620597·SID 87575912
Formula: C11H10N2O6
Molecular weight: 266.21 g/mol
Purity: >98.0%(HPLC)(N)
Reference databases: ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (2,5-dioxopyrrolidin-1-yl) 3-(2,5-dioxopyrrol-1-yl)propanoate
SMILES: C1CC(=O)N(C1=O)OC(=O)CCN2C(=O)C=CC2=O
InChIKey: JKHVDAUOODACDU-UHFFFAOYSA-N

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N-Succinimidyl 3-Maleimidopropionate is a cross-linking reagent widely used in chemical and biochemical laboratory applications. It serves as a versatile tool for connecting molecules such as proteins and polymers through covalent bonds. This reagent is particularly valuable in research settings where precise molecular interactions are required. Its dual functional groups—succinimidyl and maleimid—allow it to react with a variety of biomolecules, making it an essential component in many experimental protocols.

The chemical stability and high reactivity of N-Succinimidyl 3-Maleimidopropionate make it a preferred choice for laboratory use. It maintains its activity under various reaction conditions, including buffer solutions and organic media. Its resistance to degradation ensures consistent performance in experiments. The reagent’s ability to form strong and selective covalent bonds enhances its utility in applications requiring specificity and reliability.

In Indonesian laboratories, this reagent is commonly used in protein structure and function studies, as well as in biomedical product development. Its role in conjugate formation and molecular cross-linking is critical for advancing research in biochemistry and molecular biology. The reagent’s reliability and effectiveness make it a standard tool in both academic and industrial research environments.

TCI brochures (PDF)

Well-used Cross-linkers for Antibody-Drug Conjugates (ADC) 2024-05-28 · p. 1
Cross-linkers 2026-04-14 · p. 2
Drug Delivery System (DDS) Research Reagents 2025-01-29 · p. 3
Cancer Research Reagents 2025-04-01 · p. 9
Immunology Research Reagents 2026-06-03 · p. 11
Bioconjugation Reagents 2026-07-07 · p. 8

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Protein conjugation and labeling applications benefit from this reagent’s ability to form stable covalent bonds with proteins and amino acids.
Cross-linking studies in biochemistry rely on its dual functional groups for precise molecular attachment and structural analysis.
Polymer modification projects utilize its reactivity to link different polymer chains, enhancing material properties and functionality.
Immunological assays often incorporate this reagent to attach antigens or antibodies to solid supports for detection and analysis.
Biomedical research applications use it for developing targeted drug delivery systems and diagnostic reagents.

Brand	TCI
CAS number	55750-62-4
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes	Available in various quantities as per standard laboratory supply
Physical form	Solid or powder, depending on packaging
Storage	Store in a cool, dry place away from moisture and direct sunlight

This reagent should be stored in a cool, dry place, away from moisture and direct sunlight. It is recommended to use airtight containers to prevent exposure to air and humidity. Due to its chemical reactivity, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles. Storage conditions should maintain a stable temperature to preserve its chemical integrity. Avoid contact with incompatible substances to ensure safety in the laboratory environment. Proper labeling and storage practices are essential to maintain the reagent’s effectiveness and safety during use.

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