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TCI

CAS 64987-85-5

N-Succinimidyl 4-(N-Maleimidomethyl)cyclohexanecarboxylate TCI S0853

N-Succinimidyl 4-(N-Maleimidomethyl)cyclohexanecarboxylate TCI S0853

Chemical Identity

Other names
SMCC
CAS No.
64987-85-5
PubChem
CID 125175·SID 135727275
Formula
C16H18N2O6
Molecular weight
334.32 g/mol
Purity
>98.0%(HPLC)(qN
Reference databases
ChEBI·ChemSpider·ECHA·Wikipedia
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(2,5-dioxopyrrolidin-1-yl) 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexane-1-carboxylate
SMILES
C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)ON3C(=O)CCC3=O
InChIKey
JJAHTWIKCUJRDK-UHFFFAOYSA-N
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N-Succinimidyl 4-(N-Maleimidomethyl)cyclohexanecarboxylate is a chemical compound widely used in chemical biology for its ability to link biological molecules. This compound serves as a versatile linker and crosslinker, enabling the covalent attachment of proteins, peptides, and nucleic acids. In laboratory settings, it plays a critical role in biochemistry research, supporting applications such as immunofluorescence labeling and antigen-antibody binding studies. Its utility extends to molecular interaction analyses, where precise chemical coupling is essential for accurate results.

The compound's unique chemical structure allows it to react selectively with amino and sulfhydryl groups, making it highly effective for targeted molecular conjugation. This specificity ensures minimal interference with other molecular components, enhancing the reliability of experimental outcomes. Its stable chemical properties and strong reactivity make it a preferred choice for researchers requiring precision and consistency. These characteristics contribute to its widespread use in advanced biochemical applications.

In Indonesian laboratories, this compound is extensively utilized in biomedical, pharmacological, and biotechnological research. It supports a variety of experimental protocols, including protein labeling and molecular crosslinking. Researchers across academic institutions and research centers rely on this compound for its reliability and effectiveness in complex biochemical processes.

TCI brochures (PDF)

  • Immunofluorescence labeling where precise molecular conjugation is required for fluorescent marker attachment.
  • Antigen-antibody binding studies to facilitate the formation of stable molecular complexes.
  • Protein crosslinking experiments to investigate molecular interactions and structural changes.
  • Peptide conjugation applications for the development of targeted therapeutics and diagnostic tools.
  • Nucleic acid crosslinking to study DNA or RNA interactions in molecular biology research.

Brand TCI
CAS number 64987-85-5
Molecular formula —
Purity —
Category Chemistry > Chemical Biology > Linkers and Crosslinkers
Pack sizes Available in various quantities as per standard supplier offerings
Physical form Solid or powder, depending on formulation
Storage Store in a cool, dry place away from light and moisture

This compound should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Laboratory personnel should handle the compound with care, using appropriate personal protective equipment such as gloves and safety goggles. Due to its reactive nature, it should be stored in a secure location to avoid accidental exposure. Proper labeling of storage containers is essential for safe handling and to ensure compliance with laboratory safety protocols.

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