N-Succinimidyl 4-Benzoylbenzoate TCI S0863

Chemical Identity

CAS No.: 91990-88-4
PubChem: CID 2762595·SID 135726902
Formula: C18H13NO5
Molecular weight: 323.3 g/mol
Purity: >98.0%(HPLC)(N)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (2,5-dioxopyrrolidin-1-yl) 4-benzoylbenzoate
SMILES: C1CC(=O)N(C1=O)OC(=O)C2=CC=C(C=C2)C(=O)C3=CC=CC=C3
InChIKey: MVQNJLJLEGZFGP-UHFFFAOYSA-N

Rp 3.790.500,00

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Berat 200mg 1g

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N-Succinimidyl 4-Benzoylbenzoate is a chemical compound widely used in biochemical and organic chemistry experiments. It belongs to the category of linkers and crosslinkers, playing a crucial role in the conjugation of biological molecules such as proteins and nucleic acids. This compound enables researchers to study molecular interactions by chemically linking two molecules through specific reactions. Its versatility makes it an essential tool in various laboratory applications, supporting both fundamental and applied research.

The compound is known for its chemical stability and high reactivity, which are key factors in its preference among researchers. Its molecular structure allows it to react with amino groups, making it particularly useful in biochemical applications. The reactivity and stability ensure that it performs reliably under various experimental conditions, contributing to the accuracy and reproducibility of results. These properties make it a trusted choice for both academic and industrial research settings.

In Indonesian laboratories, N-Succinimidyl 4-Benzoylbenzoate is commonly used in biochemistry, pharmaceutical, and organic chemistry research. It is a valuable resource for institutions and universities conducting experiments that require molecular conjugation. Its availability supports the advancement of scientific research in Indonesia, particularly in fields where crosslinking and molecular interaction studies are essential.

Advantages (TCI brochure)

Benzophenones excited by UV (near 360 nm) induce hydrogen abstraction from target molecules
Reaction efficiency remains high due to reversibility of the excited state
Photoexcited benzophenones are not water-reactive

TCI brochures (PDF)

Photo-reactive Crosslinkers 2024-11-07 · p. 2
Cross-linkers 2026-04-14 · p. 4
Bioconjugation Reagents 2026-07-07 · p. 5
Reagents for Biological Research 2025-03-11 · p. 31

Related TCI products

Bioconjugation studies benefit from this compound's ability to link biomolecules, facilitating the development of targeted therapies and diagnostic tools.
Protein labeling applications utilize its reactivity with amino groups to attach fluorescent or radioactive tags for tracking molecular behavior.
Crosslinking in structural biology helps researchers study protein-protein interactions and molecular architecture in complex systems.
Drug development research employs it to create conjugates that enhance drug delivery and targeting efficiency in therapeutic applications.
Molecular interaction analysis in biochemical assays relies on its capacity to form stable linkages for studying dynamic biological processes.

From the TCI brochure

Photoaffinity labeling
Photoaffinity microarray

Brand	TCI
CAS number	91990-88-4
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Linkers and Crosslinkers
Pack sizes	Available in standard laboratory quantities
Physical form	Solid powder
Storage	Store in a cool, dry place away from light

This compound should be stored in a cool, dry environment, away from direct sunlight and sources of heat. It is recommended to keep it in a sealed container to prevent moisture absorption and maintain its chemical integrity. Proper ventilation should be ensured when handling the material to minimize exposure. Due to its reactivity, it should be handled with care using appropriate personal protective equipment. It is advisable to store it in a dedicated chemical storage cabinet to ensure safety and prevent accidental contamination. Regular inspection of storage conditions is recommended to maintain optimal performance and safety standards in the laboratory.

References cited in the TCI brochure

Günther F. Ross. Synthesis of Trifunctional PNA−Benzophenone Derivatives for Mitochondrial Targeting, Selective DNA Binding, and Photo-Cross-Linking Bioconjugate Chemistry, 2003. doi:10.1021/bc034050f
Yongwon Jung. Photoactivable Antibody Binding Protein: Site-Selective and Covalent Coupling of Antibody Analytical Chemistry, 2009. doi:10.1021/ac8014565
Alex J. Hughes. Microfluidic Western blotting Proceedings of the National Academy of Sciences, 2012. doi:10.1073/pnas.1207754110