Ethyl Bromodifluoroacetate TCI B1463

Chemical Identity

CAS No.: 667-27-6
PubChem: CID 69585·SID 87564380
Formula: C4H5BrF2O2
Molecular weight: 202.98 g/mol
Purity: >98.0%(GC)
Reference databases: ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: ethyl 2-bromo-2,2-difluoroacetate
SMILES: CCOC(=O)C(F)(F)Br
InChIKey: IRSJDVYTJUCXRV-UHFFFAOYSA-N

Rp 769.650,00

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Ethyl Bromodifluoroacetate (EBDFA), with CAS number 667-27-6, is a fluorinated building block widely used in organic chemistry for the synthesis of fluorinated compounds. This compound plays a crucial role in laboratory settings where researchers aim to develop complex molecular structures with enhanced chemical properties. Its presence in chemical reactions enables the creation of fluorinated derivatives that are essential in various scientific fields. Due to its reactivity and compatibility with multiple synthetic pathways, EBDFA is a versatile reagent that supports a wide range of chemical transformations.

One of the key reasons for its popularity is its chemical stability and reactivity under controlled conditions. These properties make it an ideal candidate for nucleophilic substitution and halogen replacement reactions, which are fundamental in organic synthesis. The presence of fluorine atoms in its structure also contributes to its unique reactivity and functional group versatility. These characteristics allow scientists to design and synthesize compounds with specific biological or material properties, making EBDFA a valuable tool in research laboratories.

In Indonesian laboratories, EBDFA is commonly used in organic chemistry research, particularly in the synthesis of fluorinated compounds. Its availability and effectiveness in supporting various chemical reactions make it a preferred choice for local researchers. The compound’s role in creating complex fluorinated structures aligns with the growing demand for advanced chemical materials in both academic and industrial settings. Its application in pharmaceutical and material sciences further highlights its importance in modern scientific research.

TCI brochures (PDF)

Difluoromethylation Reagents, Difluoromethylenation Reagents 2026-05-18 · p. 2
Fluorination Reagents, Fluorinated Building Blocks 2026-03-18 · p. 8

Related TCI products

Fluorinated Compound Synthesis: EBDFA is ideal for creating complex fluorinated structures due to its reactivity and compatibility with nucleophilic substitution reactions.
Pharmaceutical Research: The compound supports the development of fluorinated drugs, enhancing bioavailability and metabolic stability in medicinal compounds.
Organic Chemistry Reactions: EBDFA is widely used in halogen replacement and nucleophilic substitution reactions, offering efficient and selective chemical transformations.
Material Science Applications: Its fluorinated structure contributes to the development of advanced materials with unique chemical and physical properties.
Research and Development: EBDFA is a preferred reagent for laboratories aiming to explore new chemical pathways and functional group modifications.

Brand	TCI
CAS number	667-27-6
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Fluorinated Building Blocks
Pack sizes	Available in various quantities as per supplier specifications
Physical form	Liquid
Storage	Store in a cool, dry place away from light and incompatible substances

Ethyl Bromodifluoroacetate should be stored in a cool, dry environment to maintain its chemical stability. It is recommended to keep the compound in a sealed container to prevent exposure to moisture and air. Due to its reactivity, it should be stored away from strong oxidizing agents and incompatible materials. Laboratory personnel should handle the compound with appropriate personal protective equipment, including gloves and safety goggles. Proper ventilation is essential when working with this substance to minimize inhalation risks. Regular monitoring of storage conditions ensures the compound remains safe and effective for use in chemical experiments.

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