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CAS 128249-70-7

(R,R)-2,6-Bis(4-phenyl-2-oxazolin-2-yl)pyridine TCI B2219

(R,R)-2,6-Bis(4-phenyl-2-oxazolin-2-yl)pyridine TCI B2219

Chemical Identity

CAS No.
128249-70-7
PubChem
CID 2734679·SID 87565074
Formula
C23H19N3O2
Molecular weight
369.4 g/mol
Purity
>98.0%(HPLC)(T)
Reference databases
ChemSpider·ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(4R)-4-phenyl-2-[6-[(4R)-4-phenyl-4,5-dihydro-1,3-oxazol-2-yl]-2-pyridinyl]-4,5-dihydro-1,3-oxazole
SMILES
C1[C@H](N=C(O1)C2=NC(=CC=C2)C3=N[C@@H](CO3)C4=CC=CC=C4)C5=CC=CC=C5
InChIKey
HLHBIMJNCKZZQO-SFTDATJTSA-N
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(3 paragraphs. Paragraph 1 AT LEAST 70 words: what this material/instrument is and its role in the laboratory. Paragraph 2 AT LEAST 70 words: the properties that make it a preferred choice. Paragraph 3 AT LEAST 60 words: typical use context in Indonesian laboratories.)

(TCI B2219, also known as (R,R)-2,6-Bis(4-phenyl-2-oxazolin-2-yl)pyridine, is a chiral reagent widely used in asymmetric synthesis. This compound plays a crucial role in the laboratory by enabling the selective formation of chiral molecules with high enantioselectivity. It is particularly valuable in organic chemistry applications where the synthesis of enantiomerically pure compounds is essential. Its use extends to various research fields, including pharmaceutical and agrochemical development, where stereochemistry significantly impacts the biological activity of the final product. The compound is a key component in catalytic systems designed to enhance reaction efficiency and yield.

The compound is preferred due to its high chiral purity and effectiveness in promoting asymmetric reactions. Its molecular structure allows it to act as a chiral ligand, facilitating the formation of specific enantiomers by interacting with transition metal catalysts. This property makes it a reliable choice for researchers aiming to achieve high enantiomeric excess in their synthetic processes. Additionally, its stability under controlled reaction conditions ensures consistent results, making it a trusted reagent in both academic and industrial settings. The compound is also compatible with a wide range of solvents and reaction conditions, enhancing its versatility in laboratory applications.

In Indonesian laboratories, this compound is commonly used in academic and research institutions focused on organic chemistry and drug discovery. It supports the development of new compounds with specific stereochemical configurations, which are critical for pharmaceutical applications. Its availability through reliable suppliers like AMI Scientific ensures that researchers in Indonesia can access high-quality chiral reagents for their experiments. The compound is particularly valuable in projects aiming to produce bioactive molecules with precise stereochemistry.

TCI brochures (PDF)

  • Asymmetric synthesis is a key application where this compound is used to produce enantiomerically pure compounds, enhancing the efficiency of drug development processes.
  • Chiral ligand applications benefit from its ability to interact with transition metals, enabling selective catalytic reactions in organic chemistry.
  • Pharmaceutical research utilizes this compound to develop new drugs with specific stereochemistry, which is crucial for their biological activity.
  • Organic synthesis projects rely on its effectiveness in promoting stereoselective reactions, leading to the production of high-purity chiral compounds.
  • Agrochemical development uses this compound to create pesticides with enhanced activity and selectivity, improving crop protection efficiency.

Brand TCI
CAS number 128249-70-7
Molecular formula —
Purity —
Category Chemistry > Asymmetric Synthesis > Chiral Catalysts, Chiral Ligands, Chiral Reagents
Pack sizes Available in various quantities as per supplier specifications
Physical form Solid (as per standard product description)
Storage Store in a cool, dry place away from light and moisture

This compound should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical integrity. It is recommended to use airtight containers to prevent exposure to air and humidity, which could affect its stability. Laboratory personnel should handle the compound with care, using appropriate personal protective equipment such as gloves and safety goggles. It is important to ensure that the compound is kept in a secure location, away from incompatible materials. Proper labeling of storage containers is essential for safety and traceability. Regular monitoring of storage conditions will help maintain the quality and effectiveness of the compound during its shelf life.

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