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TCI

CAS 64325-78-6

N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine TCI B3103

N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine TCI B3103

Chemical Identity

Other names
Bz-DMT-dA
CAS No.
64325-78-6
PubChem
CID 2724489·SID 87559865
Formula
C38H35N5O6
Molecular weight
657.7 g/mol
Purity
>99.0%(HPLC)
Reference databases
ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
N-[9-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]purin-6-yl]benzamide
SMILES
COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H](C[C@@H](O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)O
InChIKey
LPICNYATEWGYHI-WIHCDAFUSA-N
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N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine is a complex chemical compound widely utilized in chemical biology, particularly in nucleic acid chemistry. This compound serves as a nucleotide analog with a structure similar to adenine, but with specific modifications at the N6 and 5'-O-trityl positions. It plays a crucial role in laboratory settings where precision and specificity are essential, especially in synthetic DNA and RNA applications. Its unique chemical structure allows it to interact with specific enzymes and proteins, making it a valuable tool in molecular studies.

The compound is preferred due to its high purity and stability under controlled conditions, which ensures reliable results in experimental processes. Its ability to maintain structural integrity during synthesis and functional assays makes it ideal for advanced biochemical research. Additionally, its compatibility with various analytical techniques enhances its utility in both basic and applied research. The compound’s chemical stability and functional versatility make it a go-to choice for laboratories requiring high-performance reagents.

In Indonesian laboratories, this compound is frequently used in biotechnology, pharmaceutical, and chemical biology research. It supports the development of synthetic nucleic acids, molecular interaction studies, and drug discovery initiatives. Its relevance in academic and industrial research settings underscores its importance in advancing scientific knowledge and innovation within the region.

Advantages (TCI brochure)

  • Protected nucleoside with masked amino and hydroxyl groups

  • Synthetic DNA and RNA synthesis where precise nucleotide analogs are required for creating modified nucleic acids.
  • Molecular interaction studies to investigate how nucleotides bind to enzymes and proteins in biochemical processes.
  • Nucleotide modification research to explore structural changes that affect biological activity and function.
  • Drug development projects that involve designing nucleotide-based therapeutics and understanding their mechanisms of action.
  • Biotechnology applications that require high-purity reagents for advanced genetic engineering and molecular biology experiments.

From the TCI brochure

  • Chemical synthesis of DNA and RNA

Brand TCI
CAS number 64325-78-6
Molecular formula —
Purity —
Category Chemistry > Chemical Biology > Nucleic Acid Chemistry
Pack sizes As available from supplier
Physical form Solid (as per standard chemical reagent form)
Storage Store in a cool, dry place away from light and moisture

This compound should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical integrity. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Due to its chemical complexity, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. Proper ventilation is essential when working with this material to minimize inhalation risks. The compound is best stored in a controlled laboratory setting to preserve its stability and functionality for extended periods. Regular monitoring of storage conditions ensures optimal performance in experimental applications.

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