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TCI

CAS 151-73-5

Betamethasone 21-Phosphate Disodium Salt TCI B4110

Betamethasone 21-Phosphate Disodium Salt TCI B4110

Chemical Identity

CAS No.
151-73-5
PubChem
CID 65478·SID 253661950
Formula
C22H28FNa2O8P
Molecular weight
516.4 g/mol
Purity
>98.0%(HPLC)(T)
Reference databases
ChEBI·ChemSpider·ECHA·Wikipedia
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
disodium;[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
SMILES
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]
InChIKey
PLCQGRYPOISRTQ-LWCNAHDDSA-L
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Betamethasone 21-Phosphate Disodium Salt is a chemical compound widely used in pharmaceutical research and biochemical experiments. As a phosphate derivative of betamethasone, a synthetic corticosteroid, it plays a crucial role in laboratory settings where steroid structure modification or synthesis of active compounds is required. This reagent is particularly valuable in experimental studies focused on inflammation, immunosuppression, and allergic responses. Its presence in research laboratories ensures the development of new therapeutic agents and the understanding of steroid mechanisms.

The compound is chemically stable and exhibits solubility in organic solvents such as ethyl acetate and acetone, making it highly versatile for various chemical reactions and separation processes. Its thermal stability further enhances its usability in long-term storage and under different experimental conditions. These properties contribute to its reliability and effectiveness in both academic and industrial research environments, ensuring consistent results in experimental protocols.

In Indonesian laboratories, Betamethasone 21-Phosphate Disodium Salt is commonly utilized in pharmacology, biochemistry, and pharmaceutical research. It is a key reagent in drug development projects, biological activity testing, and the study of steroid mechanisms. Its widespread use across research institutions and universities underscores its importance in advancing scientific knowledge and innovation in the field of medicinal chemistry.

  • Pharmaceutical research for the development of corticosteroid-based drugs due to its structural similarity to betamethasone.
  • Biochemical experiments requiring steroid modification or synthesis of active pharmaceutical ingredients.
  • In vitro studies on inflammatory and immunosuppressive effects of corticosteroids.
  • Drug formulation testing to evaluate the stability and solubility of steroid derivatives.
  • Mechanistic studies on steroid receptor interactions and biological activity profiling.

Brand TCI
CAS number 151-73-5
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents
Pack sizes Available in various quantities as per standard laboratory reagent packaging
Physical form Solid powder
Storage Store in a cool, dry place away from direct sunlight and moisture

Betamethasone 21-Phosphate Disodium Salt should be stored in a cool, dry environment to maintain its chemical stability and prevent degradation. It is recommended to keep the compound in a sealed container to avoid exposure to moisture and air, which can affect its integrity. Laboratory personnel should handle the reagent with care, using appropriate personal protective equipment such as gloves and safety goggles. It is important to ensure that the storage area is well-ventilated and free from potential contaminants. Proper labeling of containers is essential to prevent mix-ups and ensure safe handling during experiments. Regular monitoring of storage conditions helps maintain the quality and effectiveness of the reagent for reliable research outcomes.

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