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TCI

CAS 20898-44-6

tele-Benzyl-Nalpha-(tert-butoxycarbonyl)-L-histidine TCI B5735

tele-Benzyl-Nalpha-(tert-butoxycarbonyl)-L-histidine TCI B5735

Chemical Identity

Other names
Boc-His(Bzl)-OH
CAS No.
20898-44-6
PubChem
CID 6993429·SID 468590674
Formula
C18H23N3O4
Molecular weight
345.40 g/mol
Purity
>98.0%(T)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(2S)-3-(1-benzylimidazol-4-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
SMILES
CC(C)(C)OC(=O)NC(CC1=CN(C=N1)CC2=CC=CC=C2)C(=O)O
InChIKey
OUHPNBGKEMHUCQ-HNNXBMFYSA-N
MDL
MDL00066093
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tele-Benzyl-Nalpha-(tert-butoxycarbonyl)-L-histidine (Boc-His(Bzl)-OH) is a doubly protected histidine derivative widely used in solid-phase peptide synthesis (SPPS). The Boc group protects the alpha-amino functionality while the benzyl group protects the imidazole side chain, ensuring regioselective coupling and minimizing undesired side reactions during peptide chain assembly. This building block is essential for synthesizing bioactive peptides, protein interaction probes, and peptide-based drug candidates in both academic and pharmaceutical research settings.

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