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Description
tele-Benzyl-Nalpha-(tert-butoxycarbonyl)-L-histidine (Boc-His(Bzl)-OH) is a doubly protected histidine derivative widely used in solid-phase peptide synthesis (SPPS). The Boc group protects the alpha-amino functionality while the benzyl group protects the imidazole side chain, ensuring regioselective coupling and minimizing undesired side reactions during peptide chain assembly. This building block is essential for synthesizing bioactive peptides, protein interaction probes, and peptide-based drug candidates in both academic and pharmaceutical research settings.
