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TCI

CAS 50654-94-9

(tert-Butoxycarbonyl)-D-histidine TCI B6057

(tert-Butoxycarbonyl)-D-histidine TCI B6057

Chemical Identity

Other names
Boc-D-His-OH · Nalpha-Boc-D-histidine · Boc-D-His-OH · (R)-2-[(tert-Butoxycarbonyl)amino]-3-(1H-imidazol-4-yl)propionic Acid
CAS No.
50654-94-9
PubChem
CID 2724761·SID 468590881
Formula
C11H17N3O4
Molecular weight
255.27 g/mol
Purity
>98.0%(HPLC)(T)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(2R)-3-(1H-imidazol-5-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
SMILES
CC(C)(C)OC(=O)NC(CC1=CN=CN1)C(=O)O
InChIKey
AYMLQYFMYHISQO-MRVPVSSYSA-N
MDL
MDL00037851
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(tert-Butoxycarbonyl)-D-histidine (Boc-D-His-OH) is a protected D-histidine derivative with a Boc group attached to its amino terminus, serving as an essential building block for peptide synthesis. This high-purity reagent from TCI is commonly used in solid-phase and solution-phase peptide synthesis to introduce D-histidine residues into peptide chains, particularly for studies on stereochemical effects on biological activity. It finds broad application in peptide chemistry research, including the development of modified peptides, cyclic peptides, and peptide-based drug candidates with enhanced enzymatic stability.

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