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TCI

CAS 343864-78-8

4-Bromo-2-iodo-1-nitrobenzene TCI B6925

4-Bromo-2-iodo-1-nitrobenzene TCI B6925
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Description

TCI B6925 (CAS 343864-78-8) is 4-bromo-2-iodo-1-nitrobenzene, a trifunctional aromatic building block combining iodo, bromo and nitro groups on one ring. The iodide is normally far more reactive in palladium-catalysed cross-coupling than the bromide, enabling orthogonal, stepwise functionalisation. The nitro group both activates the ring toward nucleophilic aromatic substitution and serves as a masked amine that can be revealed by reduction, a combination frequently exploited in indole and heterocycle synthesis. TCI supplies 1 g and 5 g pack sizes; store cool, dry and protected from light, and handle nitroaromatic compounds with appropriate care in a fume hood.

Scientific References

  • Höger (1997). Synthesis of Bromo‐iodo‐hydroquinone Monoalkyl Ethers. Liebigs Annalen doi:10.1002/jlac.199719970139
  • Preetz et al. (1992). Schwingungsspektren und Normalkoordinatenanalyse der Bromo-Iodo-Osmate(IV), [OsBrnI6-n]2-, n = 0-6 / Vibrational Spectra and Normal Coordinate Analysis of Bromo-Iodo-Osmates(IV), [OsBrnI6-n]2-, n = 0-6. Zeitschrift für Naturforschung B doi:10.1515/znb-1992-1203

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.

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