TCI 1-Chlorododecane (CAS 112-52-7), also known as lauryl chloride, is a long-chain alkyl halide widely used to introduce a C12 hydrophobic chain into target molecules. Its terminal chlorine is readily displaced by amines, alcohols, thiols and phenolates, making it a staple reagent for surfactant and quaternary ammonium salt synthesis. The product is available in 25 mL and 500 mL packages for both small-scale research and routine preparative work. Handle it in a fume hood with chemical-resistant gloves and eye protection, keep it away from ignition sources, and store the tightly closed container in a cool, dry, well-ventilated place.
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- Turro et al. (1995). Mechanism of Dichlorination of n-Dodecane and Chlorination of 1-Chlorododecane Adsorbed on ZSM-5 Zeolite Molecular Sieves. A Supramolecular Structural Interpretation. Journal of the American Chemical Society doi:10.1021/ja00122a020
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