TCI C0217, 5-chloro-2-nitrobenzaldehyde (CAS 6628-86-0), pairs an aromatic aldehyde with an ortho nitro group and a ring chlorine, making it a highly adaptable synthetic starting point. The aldehyde supports imine formation, reductive amination, Wittig olefination, and Knoevenagel condensation, while nitro reduction followed by intramolecular cyclisation gives convenient access to quinoline and indole cores. The retained aryl chloride allows late-stage diversification through cross-coupling chemistry. AMI Scientific offers this TCI reagent in 5 g and 25 g research packs; consult the official product data sheet and SDS for specifications and safe handling.
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