TCI C0219, 2-chloro-5-nitrobenzaldehyde (CAS 6361-21-3), presents three orthogonal handles — an aldehyde, an aryl chloride, and a nitro group — on a single benzene ring. Researchers typically exploit the aldehyde first in condensation or reductive amination steps, then displace the chloride with nitrogen, oxygen, or sulfur nucleophiles, reserving nitro reduction for a late stage. This sequencing makes the compound well suited to fused-heterocycle construction and to focused compound-library work. AMI Scientific supplies it in 25 g and 250 g packs; please refer to the official TCI product data sheet and SDS for specifications and safety information.
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