Methyl Cyanoacetate (CAS 105-34-0) from TCI is a versatile non-heterocyclic building block widely used in synthetic organic chemistry. Its active methylene group, flanked by nitrile and ester functionalities, makes it an excellent carbon nucleophile for Knoevenagel condensations and Michael additions. Researchers commonly employ it as a precursor for pyridine, pyrimidine, coumarin, and other heterocyclic scaffolds, as well as for pharmaceutical intermediates. AMI Scientific supplies this reagent in 25 mL and 500 mL packs to suit both method development and routine synthetic work.
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- Wada et al. (2003). Calcite and Fluorite as Catalyst for the Knoevenagel Condensation of Malononitrile and Methyl Cyanoacetate under Solvent‐Free Conditions.. ChemInform doi:10.1002/chin.200314094
- Ali Talpur et al. (1994). Investigation of Methyl Methacrylate-Styrene Copolymerization Systemin the Presence of Methyl Cyanoacetate. Journal of Macromolecular Science, Part A doi:10.1080/10601329409349736
- Kaim (1996). “Bootstrap Model” for the Copolymerization of the Methyl Methacrylate-Styrene System in the Presence of Methyl Cyanoacetate. Journal of Macromolecular Science, Part A doi:10.1080/10601329608010935
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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