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TCI

CAS 109-78-4

Ethylene Cyanohydrin TCI C0450

Ethylene Cyanohydrin TCI C0450

Chemical Identity

Other names
2-Cyanoethanol · Hydracrylonitrile · 3-Hydroxypropionitrile
CAS No.
109-78-4
PubChem
CID 8011·SID 87565571
Formula
C3H5NO
Molecular weight
71.08 g/mol
Purity
>97.0%(GC)
Reference databases
ChEBI·ChemSpider·ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
3-hydroxypropanenitrile
SMILES
C(CO)C#N
InChIKey
WSGYTJNNHPZFKR-UHFFFAOYSA-N
MDL
MDL00002826
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Ethylene Cyanohydrin (CAS 109-78-4), also known as 3-hydroxypropionitrile, is a bifunctional TCI reagent bearing both hydroxyl and nitrile groups on a three-carbon chain. Its high polarity gives excellent miscibility with water and polar organic solvents, so it serves both as a synthetic intermediate and as a specialty solvent. The hydroxyl group supports esterification and etherification, while the nitrile can be hydrolyzed or reduced toward hydroxy acids and amino alcohols. AMI Scientific offers this reagent in a 25 mL pack; note that it is toxic and must be handled in a fume hood with appropriate protective equipment.

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  • KOBYAKOVA et al. (1995). ChemInform Abstract: Reaction of Ethylene Cyanohydrin with Acetic Acid.. ChemInform doi:10.1002/chin.199519080

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.