1,8-Cineole TCI C0934

Chemical Identity

Other names: 1,8-Epoxy-p-menthane · Eucalyptol
CAS No.: 470-82-6
PubChem: CID 2758·SID 87565985
Formula: C10H18O
Molecular weight: 154.25 g/mol
Purity: >98.0%(GC)
Reference databases: ChEBI·ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane
SMILES: CC1(C2CCC(O1)(CC2)C)C
InChIKey: WEEGYLXZBRQIMU-UHFFFAOYSA-N
MDL: MDL00167977

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1,8-Cineole, also known as eucalyptol, is a bicyclic monoterpenoid ether and the principal aromatic constituent of eucalyptus essential oil. Its bridged ether structure gives it good chemical stability, and it is frequently used as an analytical reference standard for the identification and quantification of eucalyptol in essential oils by GC and GC-MS. Beyond analysis, it serves as a starting material for terpenoid derivatisation and as a model compound in phytochemical and bioactivity studies. TCI supplies this flammable liquid in 25 mL, 100 mL, and 500 mL packs; keep containers tightly closed, protected from light, and away from ignition sources.

TCI brochures (PDF)

Terpenes 2025-09-22 · p. 6
Phytochemicals 2025-12-17 · p. 6

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Carman et al. (1996). 7,9-Dihydroxy-1,8-cineole and 2α,7-Dihydroxy-1,8-cineole: Two New Possum Urinary Metabolites. Australian Journal of Chemistry doi:10.1071/ch9960741
AK (2023). 1,8-Cineole an Underappreciated Anti Inflammatory Therapeutic. International Journal of Pharmacognosy & Chinese Medicine doi:10.23880/ipcm-16000238
MIYAZAWA et al. (1992). ChemInform Abstract: Biotransformation of 1,4‐Cineole to 3‐endo‐Hydroxy‐1,4‐cineole by Aspergillus niger.. ChemInform doi:10.1002/chin.199220263

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.