2-Chlorophenyl Phosphorodichloridate [Phosphorylating Agent] TCI C0976

Chemical Identity

Other names: 2-Chlorophenylphosphoryl Dichloride
CAS No.: 15074-54-1
PubChem: CID 84775·SID 87566021
Formula: C6H4Cl3O2P
Molecular weight: 245.42 g/mol
Purity: >97.0%(T)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 1-chloro-2-dichlorophosphoryloxybenzene
SMILES: C1=CC=C(C(=C1)OP(=O)(Cl)Cl)Cl
InChIKey: VLDPXPPHXDGHEW-UHFFFAOYSA-N
MDL: MDL00009704

Rp 664.650,00

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Berat 5g

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TCI C0976 2-Chlorophenyl Phosphorodichloridate (CAS 15074-54-1) is a moisture-sensitive phosphorylating agent supplied in a 5 g pack. Its two reactive P–Cl bonds react readily with alcohols and nucleoside hydroxyl groups, while the 2-chlorophenyl group acts as a removable phosphate protecting group. It is classically associated with phosphotriester approaches to oligonucleotide synthesis and with the preparation of protected phosphate esters. Use strict anhydrous technique in a fume hood, wear chemical-resistant gloves and eye protection, and keep the container tightly sealed, preferably under inert gas.