TCI C1020 2-Chloromethylquinoline Hydrochloride (CAS 3747-74-8) is a heterocyclic building block that pairs the widely used quinoline core with a reactive chloromethyl handle. Supplied as the hydrochloride salt, it is convenient to weigh and readily alkylates amines, thiols, phenols, and stabilised carbanions. Chemists apply it in medicinal chemistry libraries, fluorescent probe design, and the preparation of quinoline-based metal ligands. As an alkylating agent it should be handled in a fume hood with full personal protective equipment and stored tightly closed away from moisture, following the official TCI Safety Data Sheet.
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