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TCI

CAS 4023-34-1

Cyclopropanecarbonyl Chloride TCI C1059

Cyclopropanecarbonyl Chloride TCI C1059

Chemical Identity

CAS No.
4023-34-1
PubChem
CID 77637·SID 87566092
Formula
C4H5ClO
Molecular weight
104.53 g/mol
Purity
>97.0%(GC)(T)
Storage
0-10°C
Reference databases
ChemSpider·ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
cyclopropanecarbonyl chloride
SMILES
C1CC1C(=O)Cl
InChIKey
ZOOSILUVXHVRJE-UHFFFAOYSA-N
MDL
MDL00001277
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TCI C1059 Cyclopropanecarbonyl Chloride, CAS 4023-34-1, is a reactive acid chloride used to introduce the cyclopropanecarbonyl group into amides, esters, and aromatic substrates. The cyclopropane motif is frequently sought in medicinal chemistry for the conformational rigidity it adds to a molecule. AMI Scientific offers this TCI reagent in 25 g and 500 g pack sizes for both trial reactions and repeated preparative work. It is corrosive and readily hydrolysed, so handle it in a fume hood with dry glassware and follow the official TCI Safety Data Sheet.

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  • de Boer et al. (1992). The influence of substituents on the geometry of the cyclopropane ring. VI The molecular and crystal structures of cyclopropanecarboxylic acid and cyclopropanecarbonyl chloride. Recueil des Travaux Chimiques des Pays-Bas doi:10.1002/recl.19921110905

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.