TCI C1123 Cyanopyrazine (CAS 19847-12-2) is an electron-poor nitrogen heterocycle bearing a nitrile group directly on the pyrazine ring. The nitrile is a versatile handle that can be hydrolysed to amides or acids, reduced to aminomethyl derivatives, or converted into tetrazoles and amidoximes. These transformations make it a practical entry point to a broad family of pyrazine derivatives used in medicinal and heterocyclic chemistry. AMI Scientific offers 25 g and 500 g packs; handle in a fume hood and store cool, dry, and protected from light.
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- Narasimha Rao et al. (2003). A Comparison of Structure and Catalytic Functionality of 12-Molybdophosphoric Acid and Its Ammonium Salt in the Ammoxidation of 2-Methylpyrazine to 2-Cyanopyrazine. Catalysis Letters doi:10.1023/a:1025860009013
- HONG et al. (2006). 2-Cyanopyrazine Prepared from 2-Methylpyrazine by Catalytic Ammoxidation on MoVPO Catalyst. Chinese Journal of Chemical Engineering doi:10.1016/s1004-9541(06)60133-x
- Dhachapally et al. (2012). Metal vanadate catalysts for the ammoxidation of 2-methylpyrazine to 2-cyanopyrazine. Applied Catalysis A: General doi:10.1016/j.apcata.2012.07.029
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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