3-Chloroanisole (CAS 2845-89-8) from TCI is an aromatic ether bearing methoxy and chloro substituents in a meta relationship. The aryl chloride serves as a handle for palladium- or nickel-catalysed cross-coupling, while the methoxy group directs electrophilic substitution and can be demethylated to reveal a phenol. These complementary features make it a practical scaffold for building polysubstituted aromatics in medicinal chemistry and materials research. AMI Scientific offers this liquid reagent in a 25 g pack size for laboratory use.
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- Slocum et al. (1999). Ortho-metalation of p-chloroanisole: A media study. Tetrahedron Letters doi:10.1016/s0040-4039(99)00161-6
- Quint (2006). γ-Radiolysis of aqueous 2-chloroanisole. Radiation Physics and Chemistry doi:10.1016/j.radphyschem.2005.06.001
- Lee et al. (2007). 3-Chloroanisole for overcharge protection of a Li-ion cell. Electrochimica Acta doi:10.1016/j.electacta.2007.06.032
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
