TCI C0121 2-Chloroanisole (CAS 766-51-8) is a compact aromatic building block bearing methoxy and chloro groups in an ortho relationship. The methoxy group activates the ring toward electrophilic substitution, while the aryl chloride serves as a handle for transition metal catalyzed cross coupling. These complementary features make it useful in fine chemical, agrochemical, and pharmaceutical intermediate synthesis. TCI supplies it in a 25 g pack suited to laboratory scale experimentation.
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- Quint (2006). γ-Radiolysis of aqueous 2-chloroanisole. Radiation Physics and Chemistry doi:10.1016/j.radphyschem.2005.06.001
- Lee et al. (2007). 3-Chloroanisole for overcharge protection of a Li-ion cell. Electrochimica Acta doi:10.1016/j.electacta.2007.06.032
- Slocum et al. (1999). Ortho-metalation of p-chloroanisole: A media study. Tetrahedron Letters doi:10.1016/s0040-4039(99)00161-6
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