TCI C0122 4-Chloroanisole (CAS 623-12-1) is the para isomer of chloroanisole, offering clean and predictable aromatic reactivity. With the para position already occupied, electrophilic reactions are directed more selectively, reducing troublesome isomer mixtures. Its aryl chloride bond also makes it a convenient substrate for palladium or nickel catalyzed cross coupling studies. TCI offers the material in 25 g and 500 g packs for both exploratory and routine synthetic work.
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- Quint (2006). γ-Radiolysis of aqueous 2-chloroanisole. Radiation Physics and Chemistry doi:10.1016/j.radphyschem.2005.06.001
- Lee et al. (2007). 3-Chloroanisole for overcharge protection of a Li-ion cell. Electrochimica Acta doi:10.1016/j.electacta.2007.06.032
- Slocum et al. (1999). Ortho-metalation of p-chloroanisole: A media study. Tetrahedron Letters doi:10.1016/s0040-4039(99)00161-6
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