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Description
4-Chloro-2-fluoroaniline (TCI C1169, CAS 57946-56-2) is a halogenated aniline with fluorine ortho and chlorine para to the amino group. The ortho fluorine modulates the basicity of the amine while the para chloride offers a convenient handle for palladium-catalysed cross-coupling. Its free primary amine supports acylation, sulfonylation, diazotization, and condensation routes toward nitrogen heterocycles, making it a recurring intermediate in medicinal and agrochemical research. Available in 10 g and 25 g packs, it should be handled with gloves in a fume hood and stored sealed in a cool, dark, well-ventilated place.
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