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Description
TCI C1223 Cyclooctylamine (CAS 5452-37-9) is a primary aliphatic amine featuring an eight-membered ring that offers distinctive steric and conformational properties. Its nucleophilic amine group readily forms amides, ureas, sulfonamides, and imines, making it a practical building block for medicinal chemistry libraries. The cyclooctyl group is often used to modulate lipophilicity and to occupy hydrophobic binding pockets. AMI Scientific supplies this TCI reagent in 5 mL and 25 mL liquid pack sizes; as a corrosive amine, it should always be handled in a fume hood.
Scientific References
Khaubunsongserm et al. (2013). Bis [N-(3-tert-butylsalicylidene) cyclooctylamine] titanium dichloride activated with MAO for ethylene polymerization. European Polymer Journaldoi:10.1016/j.eurpolymj.2013.03.023
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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