TCI C1242 Diethyl Cyanophosphonate (DEPC) is a well-established coupling reagent for activating carboxylic acids toward amide and ester bond formation. It is frequently applied in peptide synthesis, where it offers effective coupling under comparatively mild conditions. The reagent is highly toxic and moisture-sensitive, and hydrolysis can release extremely hazardous gas, so it must be handled only by trained personnel in a fume hood. Available in 5 g and 25 g packs, it must be stored, used, and disposed of strictly in accordance with the official TCI safety data sheet.
TCI brochures (PDF)
- Cyanation Reagents 2024-09-17 · p. 1
- C-N Bond Formation Reactions 2025-08-07 · p. 5
- Condensing Agents 2025-11-18 · p. 5
- Amino Acids and Peptide Synthesis Reagents 2025-08-14 · p. 39
Related TCI products
- TCI D5814 13086-84-5 Di-tert-butyl Phosphonate
- TCI D4074 62999-73-9 Diethyl (1,3-Dithian-2-yl)phosphonate
- TCI D3981 133113-76-5 Dimethyl 2-(1,3-Dithiole)phosphonate
- TCI O0187 14444-77-0 Diethyl Phenyl Orthoformate
- TCI D1294 1188-33-6 N,N-Dimethylformamide Diethyl Acetal [for Esterification]
- TCI T1985 2232-08-8 1-(p-Toluenesulfonyl)imidazole
From the TCI brochure
- Conversion of Aldoximes to Nitriles
- Base (tidak disebutkan jenisnya) (CH2Cl2, rt)
| Brand | — |
|---|---|
| CAS number | — |
| Molecular formula | — |
| Purity | — |
| Category | — |
| Pack sizes | — |
| Physical form | — |
| Storage | — |
Data from the TCI brochure
| Kemasan | 5g / 25g |
|---|
Source: TCI brochure RR030 (2024-09-17)
—
- GUZMAN et al. (1997). ChemInform Abstract: A Convenient Method for the Phosphorylation of Phenols with Diethyl Cyanophosphonate.. ChemInform doi:10.1002/chin.199747196
- Guzmán et al. (1997). A Convenient Method for the Phosphorylation of Phenols with Diethyl Cyanophosphonate. Synthetic Communications doi:10.1080/00397919708005008
- Demir et al. (2009). Cyanide Ion Promoted Addition of Acylphosphonates to Diethyl Cyanophosphonate: Synthesis of Phosphonocyanohydrin O-Phosphates. Synthesis doi:10.1055/s-0029-1216634
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
References cited in the TCI brochure
- Kie-Seung Lee. An Efficient Synthesis of Nitriles from Aldoximes Using Diethyl Phosphorocyanidate under Mild Conditions Bulletin of the Korean Chemical Society, 2012. doi:10.5012/bkcs.2012.33.10.3173
Produk Terkait
-
Di-tert-butylPhosphonate TCI D5814
Regular price From Rp 848.400,00Regular price -
Diethyl(1,3-Dithian-2-yl)phosphonate TCI D4074
Regular price Rp 4.056.150,00Regular price -
Dimethyl2-(1,3-Dithiole)phosphonate TCI D3981
Regular price From Rp 5.910.450,00Regular price -
DiethylPhenylOrthoformate TCI O0187
Regular price From Rp 1.776.600,00Regular price -
N,N-DimethylformamideDiethylAcetal[forEsterification] TCI D1294
Regular price From Rp 1.060.500,00Regular price -
1-(p-Toluenesulfonyl)imidazole TCI T1985
Regular price From Rp 1.087.800,00Regular price -
4-TrifluoromethylbenzoicAnhydride TCI T1593
Regular price Rp 4.797.450,00Regular price -
2,4,6-TrichlorobenzoylChloride TCI T1413
Regular price From Rp 2.466.450,00Regular price
![N,N-Dimethylformamide Diethyl Acetal [for Esterification] (CAS 1188-33-6) - TCI D1294 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510D1294.jpg?v=1767102837&width=533)
