TCI C1321 2-Chloromethyl-1,3-dioxolane is a masked chloroacetaldehyde in which the aldehyde is protected as a cyclic acetal. The chloromethyl group alkylates alkoxides, thiolates, amines, and stabilised carbanions, while the dioxolane ring survives basic and nucleophilic conditions. Mild aqueous acid then unmasks the aldehyde for further transformations such as reductive amination or heterocycle formation. AMI Scientific supplies this TCI product in a 25 g pack; store it cool, dry, and away from acids.
Related TCI products
- TCI T2575 1193-11-9 2,2,4-Trimethyl-1,3-dioxolane
- TCI B3463 62563-07-9 2-(3-Bromopropyl)-1,3-dioxolane
- TCI B2128 87227-41-6 2-(4-Bromobutyl)-1,3-dioxolane
- TCI B2100 10602-01-4 2-(4-Bromophenyl)-1,3-dioxolane
- TCI B2098 17789-14-9 2-(3-Bromophenyl)-1,3-dioxolane
- TCI B2084 34824-58-3 2-(2-Bromophenyl)-1,3-dioxolane
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