3-Cyanothiophene (CAS 1641-09-4) from TCI is a beta-substituted thiophene building block available at AMI Scientific. The nitrile group is highly versatile, providing straightforward access to carboxylic acids, amides, primary amines, tetrazoles, and amidines. Its thiophene core is a recurring motif in both medicinal chemistry programmes and organic electronic materials such as conjugated polymers. Two pack sizes let laboratories choose between exploratory work and larger preparative synthesis.
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- Simbizi et al. (2020). Hyperfine structures of 2-cyanothiophene and 3-cyanothiophene: A quantum chemical study. Molecular Astrophysics doi:10.1016/j.molap.2020.100099
- Simbizi et al. (2020). Theoretical investigation of protonated thiophene and two of its nitrile substituted derivatives (2-cyanothiophene and 3-cyanothiophene). Physical Chemistry Chemical Physics doi:10.1039/d0cp03154b
- Li et al. (2026). High-Resolution Rotational Spectra and Molecular Structures of 2-Cyanothiophene and 3-Cyanothiophene. Journal of Molecular Structure doi:10.1016/j.molstruc.2025.144783
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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