TCI C1394 4-Chloro-7-chlorosulfonyl-2,1,3-benzoxadiazole (CAS 142246-48-8) is a bifunctional fluorescent reagent built on a benzoxadiazole core. Its chlorosulfonyl group reacts readily with amines to form stable sulfonamides, while the 4-chloro position undergoes substitution with amine or thiol nucleophiles. This dual reactivity makes it valuable for pre-column HPLC derivatisation, fluorescent labelling of peptides, and the design of molecular probes. AMI Scientific supplies it in 1 g and 5 g packs; because the reagent is moisture- and light-sensitive, careful storage is essential for reproducible results.
Related TCI products
- TCI C1337 7116-16-7 4-Chloro-2,1,3-benzoxadiazole
- TCI B4513 21510-43-0 2-(4-Bromophenyl)-5-phenyl-1,3,4-oxadiazole
- TCI A5596 664985-43-7 DAABD-Cl [=4-[2-(Dimethylamino)ethylaminosulfonyl]-7-chloro-2,1,3-benzoxadiazole] [for Proteome Analysis]
- TCI A5592 10199-89-0 NBD-Cl (=4-Chloro-7-nitro-2,1,3-benzoxadiazole) [for HPLC Labeling]
- TCI M1404 59337-92-7 Methyl 3-(Chlorosulfonyl)-2-thiophenecarboxylate
- TCI B4473 273-09-6 2,1,3-Benzoxadiazole
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![4-Chloro-7-chlorosulfonyl-2,1,3-benzoxadiazole [Bifunctional Fluorescent Reagent] (CAS 142246-48-8) - TCI C1394 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510C1394_7bfff2f7-dbc6-44eb-91d1-ef8cde3e5632.jpg?v=1768816508&width=1445)

![664985-43-7 DAABD-Cl [=4-[2-(Dimethylamino)ethylaminosulfonyl]-7-chloro-2,1,3-benzoxadiazole] [for Proteome Analysis] - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510A5596_90fe1edd-4558-44b4-b82d-7e5cd07d7fac.jpg?v=1772176844&width=533)