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TCI

CAS 142246-48-8

4-Chloro-7-chlorosulfonyl-2,1,3-benzoxadiazole [Bifunctional Fluorescent Reagent] TCI C1394

4-Chloro-7-chlorosulfonyl-2,1,3-benzoxadiazole [Bifunctional Fluorescent Reagent] TCI C1394

Chemical Identity

Other names
4-Chloro-2,1,3-benzoxadiazole-7-sulfonyl Chloride · 4-Chloro-7-chlorosulfonylbenzofurazan
CAS No.
142246-48-8
PubChem
CID 612515·SID 87566404
Formula
C6H2Cl2N2O3S
Molecular weight
253.05 g/mol
Purity
>97.0%(T)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
4-chloro-2,1,3-benzoxadiazole-7-sulfonyl chloride
SMILES
C1=C(C2=NON=C2C(=C1)Cl)S(=O)(=O)Cl
InChIKey
BPPRLMZEVZSIIJ-UHFFFAOYSA-N
MDL
MDL00191405
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TCI C1394 4-Chloro-7-chlorosulfonyl-2,1,3-benzoxadiazole (CAS 142246-48-8) is a bifunctional fluorescent reagent built on a benzoxadiazole core. Its chlorosulfonyl group reacts readily with amines to form stable sulfonamides, while the 4-chloro position undergoes substitution with amine or thiol nucleophiles. This dual reactivity makes it valuable for pre-column HPLC derivatisation, fluorescent labelling of peptides, and the design of molecular probes. AMI Scientific supplies it in 1 g and 5 g packs; because the reagent is moisture- and light-sensitive, careful storage is essential for reproducible results.

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