• 664985-43-7 DAABD-Cl [=4-[2-(Dimethylamino)ethylaminosulfonyl]-7-chloro-2,1,3-benzoxadiazole] [for Proteome Analysis] - AMI Scientific
  • 664985-43-7 DAABD-Cl [=4-[2-(Dimethylamino)ethylaminosulfonyl]-7-chloro-2,1,3-benzoxadiazole] [for Proteome Analysis] - AMI Scientific
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TCI

CAS 664985-43-7

DAABD-Cl [=4-[2-(Dimethylamino)ethylaminosulfonyl]-7-chloro-2,1,3-benzoxadiazole] [for Proteome Analysis] TCI A5596

DAABD-Cl [=4-[2-(Dimethylamino)ethylaminosulfonyl]-7-chloro-2,1,3-benzoxadiazole] [for Proteome Analysis] TCI A5596

Chemical Identity

Other names
DAABD-Cl
CAS No.
664985-43-7
PubChem
CID 44629802·SID 87558658
Formula
C10H13ClN4O3S
Molecular weight
304.75 g/mol
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
4-chloro-N-[2-(dimethylamino)ethyl]-2,1,3-benzoxadiazole-7-sulfonamide
SMILES
CN(C)CCNS(=O)(=O)C1=CC=C(C2=NON=C12)Cl
InChIKey
RJEYFWVHUXSWTA-UHFFFAOYSA-N
Rp 5.672.100,00
Rp 3.981.600,00 Rp 5.672.100,00
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Dokumen Keamanan & Mutu

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DAABD-Cl, also known as 4-[2-(Dimethylamino)ethylaminosulfonyl]-7-chloro-2,1,3-benzoxadiazole, is a specialized chemical compound used in proteome analysis within laboratory settings. It serves as a crucial reagent for protein binding and separation in biological samples, enabling researchers to isolate and analyze complex mixtures of proteins with high precision. This compound is particularly valuable in analytical chemistry, where its unique chemical properties allow for efficient and reproducible results in various protein-related experiments. Its role in enhancing the resolution of protein separation is vital for accurate and sensitive proteomic studies.

DAABD-Cl is preferred due to its chemical stability under controlled conditions and its ability to specifically interact with certain amino acid residues, such as lysine and arginine. These interactions enable strong and selective protein binding, which is essential for chromatographic techniques. The compound’s molecular structure allows it to form stable complexes with proteins, making it an effective tool for applications requiring high specificity and sensitivity. Its reliability in maintaining consistent performance across multiple experimental runs further solidifies its position as a preferred choice in proteomic research.

In Indonesian laboratories, DAABD-Cl is widely used by researchers in biochemistry, pharmacology, and biotechnology. It plays a key role in advancing the understanding of protein structure and function through its application in advanced analytical techniques. Its use in both academic and industrial research settings highlights its importance in the field of proteomics, supporting a wide range of scientific investigations and discoveries.

Advantages (TCI brochure)

  • Chlorine at the 7-position reacts specifically with SH groups
  • Reagent is non-fluorescent; DAABD derivative is strongly fluorescent
  • Dimethylamino group gives high intensity cations in electrospray ionization MS
  • Allows analysis of extremely small quantities of peptides

TCI brochures (PDF)

Related TCI products

  • Two-dimensional gel electrophoresis (2D GE) benefits from DAABD-Cl as it enhances protein separation by enabling specific binding and resolution, allowing for more detailed proteomic profiling.
  • Mass spectrometry (MS) analysis utilizes DAABD-Cl for its ability to bind proteins effectively, improving the accuracy and sensitivity of protein identification in complex samples.
  • Protein purification processes rely on DAABD-Cl to selectively bind target proteins, facilitating their isolation from biological matrices with high efficiency.
  • Biochemical research applications leverage DAABD-Cl’s specificity for amino acid residues, supporting studies on protein structure and functional interactions.
  • Analytical reagent applications in Indonesian laboratories depend on DAABD-Cl for its stability and reproducibility, ensuring reliable results in proteomic studies.

From the TCI brochure

  • Protein identification and quantification by FD-LC-MS/MS (fluorescence HPLC isolation, trypsin digestion, LC-MS/MS and MASCOT search)
  • Identification of abnormal or pathogenic proteins (expected application)

Brand TCI
CAS number 664985-43-7
Molecular formula —
Purity —
Category Analytical Chemistry > Analytical Reagents > Mass Spectrometry (MS) Reagents
Pack sizes Available in various quantities as per supplier specifications
Physical form Solid, typically in powder form
Storage Store in a cool, dry place away from light and moisture

DAABD-Cl should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. In laboratory settings, it is essential to handle the compound with appropriate personal protective equipment, such as gloves and safety goggles, to ensure safety during use. While it is generally stable under normal storage conditions, it should be kept in a secure location to prevent accidental spills or contamination. Proper labeling of storage containers is also important for safe handling and easy identification. These precautions help maintain the integrity and effectiveness of DAABD-Cl in proteomic research applications.

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Product Categories

Analytical Chemistry

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