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TCI

CAS 1858255-08-9

Succinimidyl 6-[[7-(N,N-Dimethylaminosulfonyl)-2,1,3-benzoxadiazol-4-yl]amino]hexanoate TCI S0503

Succinimidyl 6-[[7-(N,N-Dimethylaminosulfonyl)-2,1,3-benzoxadiazol-4-yl]amino]hexanoate TCI S0503

Chemical Identity

CAS No.
1858255-08-9
PubChem
CID 44629781·SID 87558319
Formula
C18H23N5O7S
Molecular weight
453.5 g/mol
Purity
>98.0%(HPLC)(N)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(2,5-dioxopyrrolidin-1-yl) 6-[[4-(dimethylsulfamoyl)-2,1,3-benzoxadiazol-7-yl]amino]hexanoate
SMILES
CN(C)S(=O)(=O)C1=CC=C(C2=NON=C12)NCCCCCC(=O)ON3C(=O)CCC3=O
InChIKey
MMPAJYBUTABRFE-UHFFFAOYSA-N
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Succinimidyl 6-[[7-(N,N-Dimethylaminosulfonyl)-2,1,3-benzoxadiazol-4-yl]amino]hexanoate is a fluorescent labeling reagent widely used in biochemical and life science research. This compound serves as a vital tool for visualizing biological molecules under fluorescence microscopes, enabling researchers to track molecular interactions and structural changes in complex samples. Its role in laboratory settings is crucial for enhancing the accuracy and clarity of experimental data, particularly in studies involving proteins, nucleic acids, and lipids. The compound is especially valuable for applications requiring high specificity and minimal background interference.

The compound is preferred due to its high reactivity, stability, and specificity. It exhibits strong fluorescence with minimal photobleaching, ensuring reliable results over extended observation periods. Its ability to covalently bind to a wide range of biomolecules makes it versatile for various labeling applications. Additionally, its chemical structure allows for efficient conjugation without altering the native properties of the target molecules. These properties make it an essential reagent for high-precision molecular imaging and analysis.

In Indonesian laboratories, this compound is commonly used in biomedical, pharmacological, and biotechnological research. Researchers rely on it for molecular detection methods, disease mechanism studies, and drug response analysis. Its availability in the local market supports the advancement of scientific research and innovation in these fields. The compound's reliability and performance make it a trusted choice among local scientists and researchers.

Advantages (TCI brochure)

  • Yellow fluorescence from DBD core
  • Active N-hydroxysuccinimide ester

TCI brochures (PDF)

  • Molecular Imaging: This compound is ideal for visualizing molecular structures and interactions due to its high fluorescence and specificity, allowing precise tracking of biomolecules in complex samples.
  • Protein Labeling: Its high reactivity enables efficient conjugation to proteins, aiding in structural analysis and functional studies of protein complexes in biological systems.
  • Nucleic Acid Analysis: The compound's ability to bind to nucleic acids makes it suitable for fluorescent labeling of DNA and RNA, facilitating detection and quantification in genetic research.
  • Enzyme Activity Monitoring: It is used to label substrates or products of enzymatic reactions, enabling real-time monitoring of enzyme activity and substrate turnover in biochemical assays.
  • Cell Signaling Studies: Its application in labeling cell surface receptors and intracellular components supports the investigation of signaling pathways and cellular responses to external stimuli.

From the TCI brochure

  • Can be labeled to amino groups

Brand TCI
CAS number 1858255-08-9
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Fluorescent Probes, Fluorescent Labels, Fluorescent Stains
Pack sizes Available in various quantities as per standard laboratory reagent packaging
Physical form Solid powder
Storage Store at room temperature, protected from light and moisture

Data from the TCI brochure

λex,maxca. 380 nm
λem,maxca. 510 nm

Source: TCI brochure LL039 (2025-11-18)

This compound should be stored in a cool, dry place away from direct sunlight and moisture to maintain its stability and fluorescence properties. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Due to its reactive nature, it should be handled with care using appropriate personal protective equipment such as gloves and safety goggles. Avoid contact with skin and eyes, and ensure proper ventilation when working with the compound. It is essential to follow standard laboratory safety protocols to minimize risks and ensure safe handling during experiments.

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