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TCI

CAS 150321-92-9

N-Succinimidyl 7-Methoxycoumarin-3-carboxylate TCI S0867

N-Succinimidyl 7-Methoxycoumarin-3-carboxylate TCI S0867

Chemical Identity

CAS No.
150321-92-9
PubChem
CID 2760554·SID 135727242
Formula
C15H11NO7
Molecular weight
317.25 g/mol
Purity
>98.0%(HPLC)(N)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(2,5-dioxopyrrolidin-1-yl) 7-methoxy-2-oxochromene-3-carboxylate
SMILES
COC1=CC2=C(C=C1)C=C(C(=O)O2)C(=O)ON3C(=O)CCC3=O
InChIKey
JMQAALOXLOSYCQ-UHFFFAOYSA-N
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N-Succinimidyl 7-Methoxycoumarin-3-carboxylate is a chemical compound widely used in biochemical and biotechnological applications within laboratory settings. This fluorescent ligand plays a crucial role in labeling and detecting biomolecules, particularly proteins and other biological structures. Its ability to covalently bind to amino groups makes it an essential tool for functional studies and molecular characterization. In research environments, it is commonly employed to investigate molecular interactions and structural properties, supporting a wide range of experimental approaches.

The compound is favored for its strong fluorescent properties, which allow for high-sensitivity detection of target molecules. This characteristic makes it ideal for use in techniques such as Western blotting, ELISA, and protein interaction studies. Its stability under standard laboratory conditions further enhances its reliability and ease of use. Researchers can confidently incorporate this compound into their workflows without concerns about degradation or loss of activity.

In Indonesian laboratories, N-Succinimidyl 7-Methoxycoumarin-3-carboxylate is extensively used in biomedical, pharmacological, and biotechnological research. Local scientists rely on this compound for molecular interaction studies and the development of more accurate detection methods. Its versatility and performance make it a preferred choice for both academic and industrial research applications.

Advantages (TCI brochure)

  • Blue fluorescence
  • Fluorescence spectra do not depend on pH

TCI brochures (PDF)

  • Protein-protein interaction mapping in complex biological systems benefits from its ability to label and track molecular interactions with high specificity.
  • Fluorescence-based structural analysis of biomolecules allows for non-invasive visualization of molecular architecture and conformational changes.
  • Development of molecular detection techniques requires a reliable fluorescent probe that maintains stability and sensitivity across various experimental conditions.
  • Protein-ligand interaction studies utilize its covalent binding properties to assess binding affinities and interaction dynamics.
  • Biomedical research applications leverage its fluorescent properties to monitor biological processes and evaluate therapeutic targets.

From the TCI brochure

  • Can be labeled to amino groups

Brand TCI
CAS number 150321-92-9
Molecular formula —
Purity —
Category Life Science > Antibodies > Antibody Supplementary Products
Pack sizes —
Physical form —
Storage Store at room temperature in a dry place away from light

Data from the TCI brochure

λex,max360 nm (pH7 buffer)
λem,max410 nm (pH7 buffer)

Source: TCI brochure LL039 (2025-11-18)

This compound should be stored at room temperature in a dry, cool environment, away from direct light to maintain its stability and fluorescent properties. It is recommended to use airtight containers to prevent moisture absorption, which could affect its performance. Due to its chemical nature, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. While it is not classified as hazardous under standard conditions, care should be taken to avoid contamination and ensure proper disposal according to local regulations. Regular monitoring of storage conditions is advised to maintain its integrity and effectiveness in research applications.

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