TCI A5597, also known as 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole, is a specialized reagent used in analytical chemistry for the detection and quantification of thiols in various samples. As an HPLC labeling reagent, it plays a crucial role in derivatization reactions, enabling the identification of thiols with high sensitivity and specificity. This compound is widely employed in laboratories for its ability to form stable complexes with thiols, facilitating accurate and reliable analytical results. Its application extends across multiple scientific disciplines, including pharmaceutical research, biochemical analysis, and environmental studies.
The unique chemical structure of TCI A5597 contributes to its high reactivity towards thiols, making it a preferred choice for derivatization processes. The presence of an aminosulfonyl group and a fluorine atom enhances its ability to react selectively with thiol groups, ensuring minimal interference from other compounds. This reagent is particularly valued for its stability and reproducibility, which are essential in achieving consistent and precise analytical outcomes. Its performance in high-performance liquid chromatography (HPLC) systems further solidifies its role as a reliable tool in modern analytical laboratories.
In Indonesian laboratories, TCI A5597 is commonly used in research related to health, environmental monitoring, and pharmaceutical development. Its application is especially relevant in the study of active pharmaceutical ingredients, environmental pollutants, and food components. The reagent's specificity and sensitivity make it an essential component in analytical workflows that require high precision and accuracy. Its use is widespread in both academic and industrial settings, supporting a wide range of analytical needs.
Related TCI products
- TCI A5595 98358-90-8 DBD-F [=4-(N,N-Dimethylaminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole] [for HPLC Labeling]
- TCI A5593 29270-56-2 NBD-F (=4-Fluoro-7-nitro-2,1,3-benzoxadiazole) [for HPLC Labeling]
- TCI A5592 10199-89-0 NBD-Cl (=4-Chloro-7-nitro-2,1,3-benzoxadiazole) [for HPLC Labeling]
- TCI A5569 163927-32-0 (S)-(+)-DBD-Py-NCS [=(S)-(+)-4-(N,N-Dimethylaminosulfonyl)-7-(3-isothiocyanatopyrrolidin-1-yl)-2,1,3-benzoxadiazole] [for HPLC Labeling]
- TCI A5568 163927-31-9 (R)-(-)-DBD-Py-NCS [=(R)-(-)-4-(N,N-Dimethylaminosulfonyl)-7-(3-isothiocyanatopyrrolidin-1-yl)-2,1,3-benzoxadiazole] [for HPLC Labeling]
- TCI A5558 156153-43-4 DBD-COCl [=4-(N,N-Dimethylaminosulfonyl)-7-(N-chloroformylmethyl-N-methylamino)-2,1,3-benzoxadiazole] [for HPLC Labeling]
- Pharmaceutical research for the analysis of active pharmaceutical ingredients and drug metabolism studies due to its ability to detect thiols with high specificity.
- Environmental monitoring to identify and quantify thiols in water and soil samples, aiding in the assessment of pollution levels and toxic substance presence.
- Biochemical analysis for the study of thiol-containing compounds in biological systems, supporting research in enzymology and metabolic pathways.
- Food safety testing to detect thiols in food samples, ensuring the quality and safety of food products for consumer health.
- Clinical diagnostics for the analysis of thiols in biological fluids, contributing to the understanding of metabolic disorders and disease progression.
| Brand | TCI |
|---|---|
| CAS number | 91366-65-3 |
| Molecular formula | — |
| Purity | — |
| Category | Analytical Chemistry > Analytical Reagents > Derivatization Reagents |
| Pack sizes | Available in standard laboratory quantities as per manufacturer specifications |
| Physical form | Solid powder or crystalline form, depending on packaging |
| Storage | — |
TCI A5597 should be stored in a cool, dry, and well-ventilated area away from direct sunlight and sources of heat. It is recommended to use airtight containers to prevent moisture absorption, which may affect its chemical stability. The reagent is generally stable under normal laboratory conditions but should be protected from prolonged exposure to air. When handling, it is advisable to use appropriate personal protective equipment such as gloves and safety goggles to ensure safety. Proper labeling of containers and adherence to standard laboratory safety protocols are essential to maintain the integrity and effectiveness of the reagent.
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