TCI C1478 Cortexolone (11-deoxycortisol, CAS 152-58-9) is a natural corticosteroid intermediate in the cortisol biosynthetic pathway. Life science laboratories use it as an analytical reference standard and as a substrate for studies of 11β-hydroxylase activity and adrenal function testing. Its 17α-hydroxy pregnane skeleton also serves as a starting point for the synthesis of steroid derivatives in medicinal chemistry. Supplied in a 1 g pack; follow the manufacturer's storage guidance, Certificate of Analysis, and Safety Data Sheet.
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- Shuvalova et al. (2003). Microbiological Transformation of Cortexolone into Hydrocortisone. ChemInform doi:10.1002/chin.200321167
- Reda F. Allam (2012). 11 β-Hydroxylation of cortexolone using immobilized Cunninghamella elegans protoplasts. AFRICAN JOURNAL OF BIOTECHNOLOGY doi:10.5897/ajb11.4135
- Paraszkiewicz et al. (1998). Cortexolone 11β-hydroxylation in protoplasts of Curvularia lunata. Journal of Biotechnology doi:10.1016/s0168-1656(98)00129-1
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