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Description
TCI C1516 2-Chloro-5-hydroxybenzotrifluoride (CAS 6294-93-5) is a fluorinated building block combining a trifluoromethyl group, an aromatic chlorine, and a phenolic hydroxyl on one ring. The phenol offers a handle for etherification and Mitsunobu-type couplings, while the aryl chloride supports palladium-catalysed cross-coupling, enabling planned stepwise elaboration. Trifluoromethyl substitution is frequently used in medicinal and agrochemical design to tune lipophilicity and metabolic stability. Supplied in 1 g and 5 g research packs; always consult the TCI Certificate of Analysis and Safety Data Sheet for the lot you receive.
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