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TCI

CAS 7787-70-4

Copper(I) Bromide TCI C2161

Copper(I) Bromide TCI C2161
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Description

TCI Copper(I) Bromide, catalog code C2161, is a monovalent copper salt that plays an important role as a catalyst and reagent in synthetic organic chemistry. In the laboratory, this compound is used as a source of active copper in a wide range of functional group transformation reactions, as a component of controlled radical polymerization catalyst systems, and as a reagent in the formation of carbon–carbon and carbon–heteroatom bonds. Its availability allows many coupling reactions to be carried out without requiring the more expensive noble metal catalysts that would otherwise be needed.

The characteristic that makes copper(I) bromide a widely preferred choice is its +1 oxidation state, which moves readily to +2 and back again, making the compound highly suitable for catalytic cycles based on single-electron transfer. The bromide ion as a ligand provides solubility and reactivity that differ from those of chloride or iodide, so researchers can tune reaction rate and selectivity by choosing the appropriate halide. The compound also forms complexes readily with nitrogen ligands such as bipyridine or multidentate amines, and these complexes are central to atom transfer radical polymerization.

In Indonesian laboratories, this material is typically found in university organic synthesis groups, polymer chemistry laboratories, and research institutions working on catalysis. It is generally used at bench scale for method development, reaction screening, and the preparation of intermediates, where a reliable copper(I) source is needed for routine coupling and polymerization work. Its role as an accessible alternative to noble metal catalysis makes it a practical staple for teaching laboratories and research groups operating under constrained reagent budgets.

Laboratory Applications

  • Atom transfer radical polymerization — the copper(I)/copper(II) redox couple, combined with nitrogen donor ligands such as bipyridine or multidentate amines, provides the reversible halogen transfer that controls chain growth.
  • Carbon–heteroatom bond formation — the compound serves as an active copper source for coupling reactions that join carbon centers to nitrogen, oxygen, or sulfur nucleophiles in synthetic sequences.
  • Carbon–carbon coupling reactions — copper(I) bromide functions as a reagent and catalyst for constructing carbon skeletons without recourse to more costly noble metal catalyst systems.
  • Functional group transformation — the salt acts as a source of active copper in substitution and interconversion reactions where bromide delivers reactivity distinct from chloride or iodide alternatives.
  • Copper complex preparation — its ready complexation with nitrogen ligands makes it a convenient starting point for preparing defined copper catalyst species for single-electron transfer chemistry.

Specifications

  • Brand: TCI
  • Catalog code: C2161
  • CAS number: 7787-70-4
  • Chemical name: Copper(I) Bromide
  • Category: Chemistry > Catalysis and Inorganic Chemistry > C-H Activation [Catalysis]
  • Storage: keep in a tightly closed container in a cool, dry place away from moisture and air

Handling and Storage

Store copper(I) bromide in tightly closed original containers in a cool, dry, well-ventilated area, protected from moisture and prolonged exposure to air, since copper(I) compounds are susceptible to oxidation toward the copper(II) state. Where extended storage or particularly sensitive work is planned, keeping the material under inert atmosphere is advisable. Handle the solid in a fume hood using gloves, safety goggles, and a laboratory coat, and avoid generating dust during weighing and transfer. Use clean, dry spatulas and glassware to prevent contamination, reseal containers promptly after use, and consult the manufacturer's safety data sheet for full hazard information and disposal requirements before beginning work.

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