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Description
4-Chloro-6-hydroxypyrimidine is a chemical compound widely used as a foundational building block in the synthesis of heterocyclic compounds. Its molecular structure consists of a pyrimidine ring with chlorine and hydroxyl groups attached at specific positions, making it a versatile intermediate in organic chemistry. In laboratory settings, this compound plays a crucial role in the development of new chemical entities, particularly in pharmaceutical and functional chemical research. Due to its structural versatility, it is frequently employed in the design and modification of complex molecular frameworks.
The compound's chemical properties, including its stability and controlled reactivity, make it a preferred choice for various synthetic applications. It exhibits good solubility in organic solvents such as ethyl acetate and acetone, which facilitates purification and reaction processes. Additionally, its ability to participate in substitution and ring-opening reactions enhances its utility in diverse chemical transformations. These characteristics ensure that it remains a reliable and efficient reagent in laboratory experiments.
In Indonesian laboratories, 4-Chloro-6-hydroxypyrimidine is commonly used in research focused on drug development, organic synthesis, and functional chemical applications. Its role in catalytic and condensation reactions further supports its importance in both academic and industrial chemical research. The compound’s reliability and effectiveness make it a valuable resource for chemists working in various scientific fields.
Laboratory Applications
Pharmaceutical research utilizes 4-Chloro-6-hydroxypyrimidine for the synthesis of novel drug molecules due to its structural versatility and reactivity.
Organic synthesis applications benefit from its ability to undergo substitution and ring-opening reactions, enabling the creation of complex heterocyclic structures.
Functional chemical development relies on this compound for its role in catalytic and condensation reactions, enhancing the efficiency of chemical transformations.
Analytical chemistry experiments use it as a reference standard for the identification and quantification of heterocyclic compounds.
Industrial chemical production incorporates it as a key intermediate in the manufacture of specialty chemicals and pharmaceutical intermediates.
Specifications
Brand: TCI
CAS number: 4765-77-9
Category: Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes: Available in various quantities as per supplier specifications
Physical form: Solid
Storage note: Store in a cool, dry place away from direct sunlight
Handling and Storage
4-Chloro-6-hydroxypyrimidine should be stored in a cool, dry environment to maintain its chemical stability. It is recommended to keep the compound in a tightly sealed container to prevent moisture absorption and contamination. Suitable storage containers include glass or high-density polyethylene vessels that are resistant to chemical degradation. In laboratory settings, it is important to handle the compound with appropriate personal protective equipment, such as gloves and safety goggles, to ensure safe handling. Avoid exposure to heat and direct sunlight, as these conditions may affect the compound’s integrity. Regular inspection of storage conditions is advised to ensure optimal preservation of the material.
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