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Description
N-Carbobenzoxyglycine Methyl Ester (N-CBZ-Glycine Methyl Ester) is a chemical compound widely used in laboratory settings for its versatility in chemical and biochemical applications. This compound is an ester derived from a carboxylic acid and an amino acid, featuring a complex molecular structure that supports its reactivity in various synthetic processes. Its role in the laboratory is critical for the synthesis of peptides and amino acid analogs, where it acts as a key intermediate. Due to its functional group reactivity, it is also employed in reactions requiring the activation of specific functional groups, making it an essential tool for organic chemists and biochemists.
The compound's chemical properties, including its stability under certain conditions and reactivity toward hydrolysis and substitution reactions, make it a preferred choice for researchers. Its molecular structure, which includes both ester and carboxylate groups, enables it to participate in a wide range of chemical transformations. These characteristics make it particularly suitable for applications involving the modification of molecules and the synthesis of complex compounds. Its reactivity and structural versatility have made it a staple in many research laboratories, especially those focused on molecular design and drug development.
In Indonesian laboratories, N-Carbobenzoxyglycine Methyl Ester is commonly used in research related to chemistry, biochemistry, and pharmacology. It is frequently employed in basic research and development projects by academic institutions and research centers. Its utility in synthesizing complex organic molecules and its role in peptide chemistry make it a valuable resource for scientists working on molecular modifications and drug discovery initiatives.
Laboratory Applications
Peptide Synthesis: This compound is ideal for peptide synthesis due to its ability to activate carboxylate groups, facilitating the formation of peptide bonds in solid-phase peptide synthesis techniques.
Amino Acid Analog Development: It serves as a building block for creating amino acid analogs, which are crucial for studying protein structures and functions in biochemical research.
Functional Group Activation: Its reactivity toward hydrolysis and substitution reactions makes it suitable for activating specific functional groups in organic synthesis, enhancing reaction efficiency.
Molecular Modification Studies: Researchers use it to modify molecular structures, enabling the study of how structural changes affect biological activity and chemical behavior.
Drug Discovery Research: Its role in synthesizing complex organic compounds makes it a valuable tool in pharmaceutical research, aiding in the development of new therapeutic agents.
Specifications
Brand: TCI
CAS number: 1212-53-9
Category: Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes: Available in various quantities as per standard laboratory supply
Physical form: Solid, crystalline powder
Storage note: Store in a cool, dry place away from moisture and direct sunlight
Handling and Storage
This compound should be stored in a cool, dry environment to maintain its chemical stability. It is recommended to keep it in a tightly sealed container to prevent exposure to moisture and air, which can lead to hydrolysis. Due to its reactivity, it should be handled in a well-ventilated area, and appropriate personal protective equipment such as gloves and safety goggles should be worn. Avoid direct contact with skin and eyes, and ensure that it is stored away from incompatible substances. Regular monitoring of storage conditions is advised to ensure the integrity of the compound during long-term use in laboratory settings.
