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Description
TCI C2942 is Cyproterone Acetate, a synthetic steroid compound supplied as a pharmaceutical research reagent for experimental laboratory use. The molecule belongs to the modified pregnane steroid family and is widely documented in the endocrinology literature as both an antiandrogenic compound and a progestin. In a research setting, this material serves as a test compound for hormone receptor investigations, as an analytical reference substance during the development of steroid assay methods, and as a subject of medicinal chemistry studies examining the relationship between steroid structure and biological activity.
The properties that make this material valuable to researchers centre on its rigid, stereochemically defined four-ring steroid framework, complemented by an acetate ester group and a characteristic substitution pattern that distinguishes it from naturally occurring steroid hormones. Because the ring skeleton is conformationally rigid, the spatial orientation of its functional groups remains highly consistent from experiment to experiment, which makes the compound well suited to receptor binding studies and molecular modelling work. As a steroid, it is generally a crystalline solid with limited solubility in water but dissolves in organic solvents such as ethanol or dimethyl sulfoxide.
Within Indonesian laboratories, this reagent is typically handled in university pharmacy and pharmaceutical chemistry departments, biomedical and endocrinology research groups, and analytical method development units that work with steroid compounds. It is used strictly for experimental purposes, prepared as stock solutions in a suitable organic solvent before dilution into working systems, and applied in receptor studies, comparative analytical runs, and structure–activity investigations conducted under standard laboratory protocols.
Laboratory Applications
Hormone receptor binding studies — the rigid steroid skeleton gives a consistent spatial arrangement of functional groups, making interaction data with receptor preparations reproducible between experimental runs.
Analytical reference material for steroid assay development — serves as a comparison substance when chromatographic or spectroscopic methods for steroid compounds are being established and validated in the laboratory.
Medicinal chemistry structure–activity research — its distinctive substitution pattern relative to natural steroid hormones makes it a useful reference point for studying how structural modification affects biological activity.
Molecular modelling and computational chemistry work — the stereochemically defined, conformationally rigid four-ring framework provides reliable geometry input for docking simulations and comparative structural analysis studies.
Endocrinology teaching and experimental investigation — widely documented in the endocrinology literature as an antiandrogen and progestin, giving researchers ample published context to design and interpret experimental work.
Specifications
Brand: TCI
CAS number: 427-51-0
Category: Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents (for Experimental Use)
Product code: C2942
Physical form: crystalline solid; limited solubility in water, soluble in organic solvents such as ethanol or dimethyl sulfoxide
Pack sizes: available in standard research quantities — please refer to the catalogue listing for the packaging options offered
Storage: keep in a tightly closed container in a cool, dry place away from light
Handling and Storage
Store the material in its original tightly closed container, in a cool, dry location protected from direct light and moisture, and follow the storage instructions printed on the product label and safety data sheet. Amber glass vials or the supplier's original packaging are appropriate containers; avoid transferring the solid into containers that do not seal properly. Handle the compound in a well-ventilated area or fume hood using gloves, safety glasses, and a laboratory coat, and avoid generating dust when weighing the crystalline solid. Stock solutions prepared in ethanol or dimethyl sulfoxide should be clearly labelled with the solvent, concentration, and preparation date, kept tightly capped, and handled only by trained personnel. This product is intended for experimental laboratory use only and is not for human or veterinary application; dispose of residues and contaminated consumables through the laboratory's established chemical waste procedures.
